SCHEMBL276243

SCHEMBL276243

Cc1ccc(Oc2cccc(C(C)(C)c3cccc(Oc4ccc(C)c(C)c4)c3)c2)cc1C

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.41
GFER P55789 2/20 0.41
LMNA P02545 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
SMN1; SMN2 Q16637 3/20 0.41
MEN1 O00255 2/20 0.41
MAPT P10636 2/20 0.41
HPGD P15428 1/20 0.41
ALDH1A1 P00352 3/20 0.40
DRD2 P14416 1/20 0.40
DRD4 P21917 1/20 0.40
DRD3 P35462 1/20 0.40
HTR2A P28223 1/20 0.40
SLC6A4 P31645 1/20 0.40
HAO1 Q9UJM8 1/20 0.39
ESR1 P03372 2/20 0.39
ESR2 Q92731 1/20 0.39
CYP2C9 P11712 2/20 0.39
CYP3A4 P08684 1/20 0.39
CYP2C19 P33261 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16604045 0.84 KMT2A (0.44) KMT2AGFERLMNAL3MBTL1SMN1; SMN2
SCHEMBL21701049 0.84 ALDH1A1 (0.49) KMT2ALMNAL3MBTL1MEN1MAPT
SCHEMBL16604058 0.83 ALDH1A1 (0.54) KMT2AGFERLMNAL3MBTL1SMN1; SMN2
SCHEMBL47863 0.83 KMT2A (0.49) KMT2AGFERLMNAL3MBTL1SMN1; SMN2
SCHEMBL30587868 0.82 KMT2A (0.52) KMT2AGFERLMNAL3MBTL1SMN1; SMN2
SCHEMBL9455443 0.82 KMT2A (0.52) KMT2AGFERLMNAL3MBTL1SMN1; SMN2
SCHEMBL13310389 0.81 LTA4H (0.50) KMT2AGFERSMN1; SMN2MEN1MAPT
SCHEMBL19341420 0.81 HTT (0.47) KMT2AGFERL3MBTL1SMN1; SMN2MEN1
SCHEMBL12792078 0.79 KMT2A (0.45) KMT2AGFERLMNAL3MBTL1SMN1; SMN2
SCHEMBL30933053 0.79 ALDH1A1 (0.66) KMT2AGFERSMN1; SMN2MEN1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210284596-A1 DIAMINE COMPOUND, METHOD FOR MANUFACTURING THE SAME, AND APPLICATIONS THEREOF DAXIN MATERIALS CORP. (TW) 2021-09-16 US disclosed
US-20160187776-A1 COMPOUND FOR SEMICONDUCTOR PACKAGE, PHOTOSENSITIVE RESIN COMPOSITION INCLUDING THE SAME AND SEMICONDUCTOR PACKAGE STRUCTURE THEREOF GTA ELECTRONICS CO., LTD (TW) 2016-06-30 US disclosed
US-20160187776-A1 COMPOUND FOR SEMICONDUCTOR PACKAGE, PHOTOSENSITIVE RESIN COMPOSITION INCLUDING THE SAME AND SEMICONDUCTOR PACKAGE STRUCTURE THEREOF GTA ELECTRONICS CO., LTD (TW) 2016-06-30 US disclosed
US-8133931-B2 Acrylate nanocomposite material NATIONAL TAIWAN UNIVERSITY (TW) 2012-03-13 US disclosed
US-8133931-B2 Acrylate nanocomposite material NATIONAL TAIWAN UNIVERSITY (TW) 2012-03-13 US disclosed
US-20100113638-A1 Acrylate Nanocomposite Material NATIONAL TAIWAN UNIVERSITY (TW) 2010-05-06 US disclosed
US-20100113638-A1 Acrylate Nanocomposite Material NATIONAL TAIWAN UNIVERSITY (TW) 2010-05-06 US disclosed
US-20080021193-A1 Process of manufacturing DOPO derivatives for printed circuit board and low-earth orbit spacecraft applications NATIONAL CHUNGHSING UNIVERSITY 2008-01-24 US disclosed
US-20080021193-A1 Process of manufacturing DOPO derivatives for printed circuit board and low-earth orbit spacecraft applications NATIONAL CHUNGHSING UNIVERSITY 2008-01-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210284596-A1 DIAMINE COMPOUND, METHOD FOR MANUFACTURING THE SAME, AND APPLICATIONS THEREOF AOC1, C9, PYM1 KMT2A 661/4885GFER 2110/4885LMNA 710/4885
US-20080021193-A1 Process of manufacturing DOPO derivatives for printed circuit board and low-earth orbit spacecraft applications DAO, DDT, PPOX KMT2A 1855/4885GFER 340/4885LMNA 1191/4885
US-20160187776-A1 COMPOUND FOR SEMICONDUCTOR PACKAGE, PHOTOSENSITIVE RESIN COMPOSITION INCLUDING THE SAME AND SEMICONDUCTOR PACKAGE STRUCTURE THEREOF SEM1, RER1, ASH2L KMT2A 581/4885GFER 2425/4885LMNA 4128/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.