Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA3 | P07451 | 1/20 | 0.34 |
| ▸ | CA4 | P22748 | 1/20 | 0.34 |
| ▸ | CA6 | P23280 | 1/20 | 0.34 |
| ▸ | CA5A | P35218 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9547534 | 0.79 | L3MBTL1 (0.36) | LMNACA12CA1CA2CA3 | |
| SCHEMBL27855514 | 0.76 | SIGMAR1 (0.35) | CA12CA1CA2CA9 | |
| SCHEMBL668536 | 0.65 | HTR1A (0.60) | LMNATSHR | |
| SCHEMBL1954342 | 0.64 | TRIM24 (0.33) | — | |
| SCHEMBL3687461 | 0.63 | KMT2A (0.44) | LMNACA12CA2CA9 | |
| Carbamic Acid SCHEMBL15287821 | 0.63 | SETD7 (0.36) | LMNA | |
| SCHEMBL1053985 | 0.62 | ALDH1A1 (0.37) | LMNACA12CA1CA2CA3 | |
| SCHEMBL17504448 | 0.61 | KDM4E (0.54) | TSHR | |
| SCHEMBL327614 | 0.61 | BLM (0.47) | LMNATSHR | |
| SCHEMBL28023530 | 0.61 | L3MBTL1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100387598-C | Pyrazolo[3,4-b]pyridine compounds, and their use as phosphodiesterase inhibitors | GLAXO GROUP LTD (GB) | 2008-05-14 | — | — | CN | disclosed |
| CN-1694882-A | Pyrazolo[3,4-b]pyridine compounds, and their use as phosphodiesterase inhibitors | GLAXO GROUP LTD (GB) | 2005-11-09 | — | — | CN | disclosed |