Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K3 | Q8IVH8 | 2/20 | 0.55 |
| ▸ | MET | P08581 | 3/20 | 0.52 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.44 |
| ▸ | NEK2 | P51955 | 3/20 | 0.41 |
| ▸ | PLK1 | P53350 | 2/20 | 0.41 |
| ▸ | AURKA | O14965 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.41 |
| ▸ | TTK | P33981 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 2/20 | 0.40 |
| ▸ | FYN | P06241 | 2/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.38 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.38 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL487859 | 0.86 | MAP4K3 (0.58) | MAP4K3METMAP4K4PLK1IDO1 | |
| SCHEMBL30454707 | 0.86 | MAP4K3 (0.58) | MAP4K3METMAP4K4PLK1IDO1 | |
| SCHEMBL27629924 | 0.83 | MET (0.56) | MAP4K3METMAP4K4FYNPDGFRB | |
| SCHEMBL30453136 | 0.83 | MAP4K3 (0.55) | MAP4K3METMAP4K4NEK2PLK1 | |
| SCHEMBL30453475 | 0.82 | MAP4K4 (0.69) | MAP4K3METMAP4K4MAOB | |
| SCHEMBL488215 | 0.82 | MAP4K4 (0.69) | MAP4K3METMAP4K4MAOB | |
| SCHEMBL27629997 | 0.79 | MET (0.61) | MAP4K3METMAP4K4NEK2PIK3C3 | |
| SCHEMBL488094 | 0.78 | MAP4K3 (0.52) | MAP4K3METMAP4K4FYN | |
| SCHEMBL27630151 | 0.77 | MET (0.48) | MAP4K3METMAP4K4FYNPDGFRB | |
| SCHEMBL488609 | 0.77 | MAP4K3 (0.52) | MAP4K3METMAP4K4NEK2PLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1777427-A | Aminoheteroaryl compounds as protein kinase inhibitors | SUGEN INC (US) | 2006-05-24 | — | — | CN | disclosed |