Methacrylic Acid

Methacrylic Acid

SCHEMBL27630262

C=C(C)C(=O)O.CC1CCc2c(ccc3c2ccc2ccccc23)C1

nearest known ligand 0.39

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.38
CYP2D6 P10635 1/20 0.38
CYP2C9 P11712 1/20 0.38
CYP2C19 P33261 1/20 0.38
HIF1A Q16665 1/20 0.38
HTR1A P08908 2/20 0.37
HTR7 P34969 2/20 0.37
NFKB1 P19838 1/20 0.37
NFKB2 Q00653 1/20 0.37
RELA Q04206 1/20 0.37
ALDH1A1 P00352 4/20 0.36
MAPT P10636 3/20 0.36
HPGD P15428 1/20 0.36
KDM4E B2RXH2 2/20 0.36
ANPEP P15144 1/20 0.35
LCK P06239 1/20 0.35
FYN P06241 1/20 0.35
ADORA3 P0DMS8 1/20 0.35
ACHE P22303 1/20 0.35
SLC6A2 P23975 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methacrylic Acid SCHEMBL28226348 0.94 CYP1A2 (0.34) CYP1A2CYP2D6CYP2C9CYP2C19HIF1A
SCHEMBL27574172 0.87 HTR7 (0.45) CYP1A2HTR1AHTR7ALDH1A1MAPT
Methacrylic Acid SCHEMBL28204534 0.86 HCAR2 (0.36) CYP1A2CYP2D6CYP2C9CYP2C19HIF1A
Fluoride SCHEMBL27587185 0.86 HTR7 (0.44) CYP1A2HTR1AHTR7ALDH1A1MAPT
Methacrylic Acid SCHEMBL27630245 0.85 LNPEP (0.37) CYP1A2CYP2D6CYP2C9CYP2C19HIF1A
Methacrylic Acid SCHEMBL27650287 0.85 MAPT (0.39) CYP1A2CYP2D6CYP2C9CYP2C19HIF1A
Methacrylic Acid SCHEMBL27650291 0.85 NFKB1 (0.36) CYP1A2CYP2D6CYP2C9CYP2C19HIF1A
Methacrylic Acid SCHEMBL27340472 0.81 ALDH1A1 (0.42) CYP1A2ALDH1A1MAPTHPGDKDM4E
Methacrylic Acid SCHEMBL31218471 0.81 ALDH1A1 (0.42) CYP1A2ALDH1A1MAPTHPGDKDM4E
Furan SCHEMBL28225333 0.81 HTR7 (0.38) CYP1A2CYP2D6CYP2C9CYP2C19HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100582131-C Fumaric diester copolymer TOSO KK 2010-01-20 CN disclosed
CN-1814639-A Daip TOSO KK (JP) 2006-08-09 CN disclosed