Methacrylic Acid

Methacrylic Acid

SCHEMBL27650291

C=C(C)C(=O)O.CC(C)CC1CCc2c(ccc3c2ccc2ccccc23)C1

nearest known ligand 0.39

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NFKB1 P19838 4/20 0.36
NFKB2 Q00653 4/20 0.36
RELA Q04206 4/20 0.36
LNPEP Q9UIQ6 3/20 0.34
PTGIR P43119 5/20 0.33
ABCB1 P08183 1/20 0.32
ABCG2 Q9UNQ0 1/20 0.32
CYP1A2 P05177 2/20 0.32
CYP2D6 P10635 1/20 0.32
CYP2C9 P11712 1/20 0.32
CYP2C19 P33261 1/20 0.32
HIF1A Q16665 1/20 0.32
ALDH1A1 P00352 2/20 0.32
MAPT P10636 2/20 0.32
HPGD P15428 1/20 0.32
ANPEP P15144 1/20 0.32
LCK P06239 1/20 0.32
FYN P06241 1/20 0.32
ADORA3 P0DMS8 1/20 0.32
ACHE P22303 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methacrylic Acid SCHEMBL27630245 0.88 LNPEP (0.37) NFKB1NFKB2RELALNPEPPTGIR
Methacrylic Acid SCHEMBL27630262 0.85 CYP1A2 (0.38) NFKB1NFKB2RELACYP1A2CYP2D6
Methacrylic Acid SCHEMBL27650365 0.84 HTR7 (0.34) NFKB1NFKB2RELAPTGIRCYP1A2
Methacrylic Acid SCHEMBL27650290 0.82 NFKB1 (0.34) NFKB1NFKB2RELACYP1A2CYP2D6
Methacrylic Acid SCHEMBL28226348 0.81 CYP1A2 (0.34) NFKB1NFKB2RELACYP1A2CYP2D6
Methacrylic Acid SCHEMBL28204534 0.81 HCAR2 (0.36) NFKB1NFKB2RELACYP1A2CYP2D6
Methacrylic Acid SCHEMBL27650287 0.80 MAPT (0.39) NFKB1NFKB2RELACYP1A2CYP2D6
SCHEMBL28990053 0.78 HTR7 (0.36) NFKB1NFKB2RELACYP1A2CYP2D6
Methacrylic Acid SCHEMBL31218471 0.76 ALDH1A1 (0.42) CYP1A2ALDH1A1MAPTHPGDLCK
Methacrylic Acid SCHEMBL27340472 0.76 ALDH1A1 (0.42) CYP1A2ALDH1A1MAPTHPGDLCK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100582131-C Fumaric diester copolymer TOSO KK 2010-01-20 CN disclosed
CN-1814639-A Daip TOSO KK (JP) 2006-08-09 CN disclosed