Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.36 |
| ▸ | PTGES | O14684 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.34 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27653935 | 0.74 | CYP1A2 (0.42) | KDM4ETAAR1CYP1A2MAPK1CASP1 | |
| SCHEMBL11050965 | 0.72 | ADORA3 (0.51) | KDM4ETAAR1PIN1PTGESLMNA | |
| SCHEMBL27653921 | 0.72 | HPGD (0.58) | KDM4ECYP1A2MAPK1CASP1CYP2C19 | |
| SCHEMBL4802255 | 0.72 | SMN1; SMN2 (0.49) | KDM4ECYP1A2MAPK1CASP1CYP2C19 | |
| SCHEMBL11054392 | 0.72 | SMN1; SMN2 (0.49) | KDM4EPIN1RAB9AKMT2AMEN1 | |
| SCHEMBL27653989 | 0.69 | TAAR1 (0.62) | KDM4ETAAR1CYP1A2MAPK1CASP1 | |
| SCHEMBL27633486 | 0.68 | ALDH1A1 (0.65) | PIN1ALDH1A1HPGD | |
| SCHEMBL27488851 | 0.66 | LMNA (0.43) | KDM4ECYP1A2MAPK1CYP2C19LMNA | |
| SCHEMBL2337944 | 0.65 | PIN1 (0.45) | PIN1RAB9AKMT2ANR4A2MEN1 | |
| SCHEMBL6503776 | 0.64 | PIN1 (0.50) | KDM4ECYP1A2MAPK1CASP1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100427472-C | Aryl-heteroaromatic compounds, compositions containing them and their use | AVENTIS PHARMA SA (FR) | 2008-10-22 | — | — | CN | claimed |
| CN-1829697-A | Aryl-heteroaromatic products, compositions containing same and use thereof | AVENTIS PHARMA SA (FR) | 2006-09-06 | — | — | CN | claimed |
| CN-100427472-C | Aryl-heteroaromatic compounds, compositions containing them and their use | AVENTIS PHARMA SA (FR) | 2008-10-22 | — | — | CN | disclosed |
| CN-1829697-A | Aryl-heteroaromatic products, compositions containing same and use thereof | AVENTIS PHARMA SA (FR) | 2006-09-06 | — | — | CN | disclosed |