Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2B | P41595 | 2/20 | 0.39 |
| ▸ | DAPK1 | P53355 | 1/20 | 0.39 |
| ▸ | STAT3 | P40763 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7640481 | 0.75 | HTR2B (0.47) | HTR2BSTAT3MAOASMN1; SMN2ALDH1A1 | |
| SCHEMBL4163078 | 0.73 | MAOA (0.43) | DAPK1STAT3MAOASMN1; SMN2ALDH1A1 | |
| SCHEMBL251787 | 0.70 | STAT3 (0.43) | DAPK1STAT3MAOASMN1; SMN2ALDH1A1 | |
| SCHEMBL7865654 | 0.68 | TRPA1 (0.41) | DAPK1MAOASMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL28882144 | 0.67 | STAT3 (0.56) | STAT3ALDH1A1HPGDHSD17B10CA2 | |
| SCHEMBL29700277 | 0.67 | PGAM1 (0.44) | STAT3MAOASMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL6155652 | 0.67 | PGAM1 (0.44) | STAT3MAOASMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL9829248 | 0.67 | CA2 (0.50) | MAOASMN1; SMN2ALDH1A1MAPTTSHR | |
| Hydroxyamine SCHEMBL28237907 | 0.65 | ALDH1A1 (0.60) | SMN1; SMN2ALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL30442890 | 0.65 | ALDH1A1 (0.67) | MAOASMN1; SMN2ALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102883709-A | Combinations of preservative compositions for ophthalmic formulations | ALLERGAN INC | 2013-01-16 | — | — | CN | disclosed |
| CN-102883708-A | Combinations of preservatives for ophthalmic compositions | ALLERGAN INC | 2013-01-16 | — | — | CN | disclosed |
| CN-100528139-C | Preserved ophthalmic compositions | ALLERGAN INC (US) | 2009-08-19 | — | — | CN | disclosed |
| CN-1794973-A | preservative composition for eyes | ALLERGAN INC (US) | 2006-06-28 | — | — | CN | disclosed |