Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 3/20 | 0.48 |
| ▸ | LRRK2 | Q5S007 | 9/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3139131 | 0.84 | HTR6 (0.67) | HTR6LRRK2KDM4EGAAMAPT | |
| SCHEMBL2762557 | 0.80 | HTR6 (0.56) | HTR6LRRK2KDM4EMEN1ALDH1A1 | |
| SCHEMBL2762828 | 0.79 | POLB (0.56) | HTR6MEN1MAPTKMT2ACYP3A4 | |
| SCHEMBL1841372 | 0.78 | SLC6A7 (0.52) | KDM4EALDH1A1GAAMAPTMAPK1 | |
| SCHEMBL4671542 | 0.78 | ALOX5 (0.54) | KDM4EALDH1A1MAPTALOX12MAPK1 | |
| SCHEMBL4673297 | 0.77 | MAPT (0.50) | KDM4EMEN1ALDH1A1TP53GAA | |
| SCHEMBL14852797 | 0.77 | HTR6 (0.45) | HTR6LRRK2KDM4EMEN1ALDH1A1 | |
| SCHEMBL4801336 | 0.76 | GHSR (0.54) | HTR6LRRK2MAPTKMT2ASLC6A4 | |
| SCHEMBL4801345 | 0.76 | GHSR (0.54) | HTR6LRRK2MAPTKMT2ASLC6A4 | |
| SCHEMBL2762254 | 0.76 | ALDH1A1 (0.44) | KDM4EMEN1ALDH1A1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2320897-B1 | COMPOSITIONS AND METHODS OF TREATING AMYLOID DISEASE | TREVENTIS CORP (US) | 2014-01-15 | — | — | EP | disclosed |
| WO-2010025375-A1 | COMPOSITIONS AND METHODS OF TREATING AMYLOID DISEASE | TREVENTIS CORPORATION (US) | 2010-03-04 | — | — | WO | disclosed |