SCHEMBL7062479

SCHEMBL7062479

c1ccc(CN2CCNCCNCCNCC2)cc1

nearest known ligand 0.96

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 4/20 0.96
CXCR4 P61073 10/20 0.67
MEN1 O00255 2/20 0.67
KMT2A Q03164 2/20 0.67
CHRM2 P08172 1/20 0.67
CHRM1 P11229 1/20 0.67
ADRA2C P18825 1/20 0.67
CCR2 P41597 1/20 0.67
CXCL12 P48061 1/20 0.67
BLM P54132 1/20 0.67
TDP1 Q9NUW8 1/20 0.67
HRH3 Q9Y5N1 1/20 0.67
ALDH1A1 P00352 1/20 0.66
CYP2C9 P11712 1/20 0.66
TSHR P16473 1/20 0.66
CYP2C19 P33261 1/20 0.66
HIF1A Q16665 1/20 0.66
MC4R P32245 1/20 0.57
DRD4 P21917 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Piperazine SCHEMBL28115310 1.00 SIGMAR1 (0.96) SIGMAR1CXCR4MEN1KMT2ACHRM2
SCHEMBL10063607 1.00 SIGMAR1 (0.96) SIGMAR1CXCR4MEN1KMT2ACHRM2
Hydrochloric Acid SCHEMBL8034018 0.98 SIGMAR1 (0.92) SIGMAR1CXCR4MEN1KMT2ACHRM2
SCHEMBL9538814 0.98 SIGMAR1 (0.92) SIGMAR1CXCR4MEN1KMT2ACHRM2
Bromide SCHEMBL21961924 0.98 SIGMAR1 (0.92) SIGMAR1CXCR4MEN1KMT2ACHRM2
SCHEMBL6138636 0.98 SIGMAR1 (1.00) SIGMAR1CXCR4MEN1KMT2ACHRM2
SCHEMBL83548 0.98 SIGMAR1 (1.00) SIGMAR1CXCR4MEN1KMT2ACHRM2
SCHEMBL152631 0.98 SIGMAR1 (1.00) SIGMAR1CXCR4MEN1KMT2ACHRM2
SCHEMBL276363 0.98 SIGMAR1 (1.00) SIGMAR1CXCR4MEN1KMT2ACHRM2
Benzene SCHEMBL27761330 0.98 SIGMAR1 (1.00) SIGMAR1CXCR4MEN1KMT2ACHRM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4351653-A1 NON-PEPTIDE TARGETED THERAPEUTICS AND USES THEREOF Radionetics Oncology, Inc. (US) 2024-04-17 EP claimed
WO-2022261221-A1 NON-PEPTIDE TARGETED THERAPEUTICS AND USES THEREOF Crinetics Pharmaceuticals, Inc. (US) 2022-12-15 WO claimed
EP-3256164-A2 MULTI-SPECIFIC ANTIBODIES WITH AFFINITY FOR HUMAN A33 ANTIGEN AND DOTA METAL COMPLEX AND USES THEREOF Memorial Sloan Kettering Cancer Center (US) 2017-12-20 EP claimed
WO-2016130539-A2 MULTI-SPECIFIC ANTIBODIES WITH AFFINITY FOR HUMAN A33 ANTIGEN AND DOTA METAL COMPLEX AND USES THEREOF MEMORIAL SLOAN KETTERING CANCER CENTER (US) 2016-08-18 WO claimed
EP-0815091-A1 POLYAZACYCLOALKANE COMPOUNDS NYCOMED IMAGING AS (NO) 1998-01-07 EP claimed
US-5705637-A Polyazacycloalkane compounds NYCOMED IMAGING AS (NO) 1998-01-06 US claimed
US-5677446-A Polyazacycloalkane compounds NYCOMED IMAGING AS (NO) 1997-10-14 US claimed
WO-1996028433-A1 POLYAZACYCLOALKANE COMPOUNDS NYCOMED IMAGING A.S (NO) 1996-09-19 WO claimed
US-20260109765-A1 MULTI-SPECIFIC ANTIBODIES WITH AFFINITY FOR HUMAN A33 ANTIGEN AND DOTA METAL COMPLEX AND USES THEREOF MEMORIAL SLOAN KETTERING CANCER CENTER (US) 2026-04-23 US disclosed
US-20250295794-A1 MODULAR SELF ASSEMBLY DISASSEMBLY (SADA) TECHNOLOGIES MEMORIAL SLOAN KETTERING CANCER CENTER (US) 2025-09-25 US disclosed
US-12343401-B2 Modular self assembly disassembly (SADA) technologies MEMORIAL SLOAN KETTERING CANCER CENTER (US) 2025-07-01 US disclosed
US-11858993-B2 Multi-specific antibodies with affinity for human A33 antigen and DOTA metal complex and uses thereof MEMORIAL SLOAN KETTERING CANCER CENTER (US) 2024-01-02 US disclosed
CN-117247552-A Mesoporous polyphosphazene microsphere and preparation method thereof 陕西中医药大学 2023-12-19 CN disclosed
WO-2023139203-A1 COMPLEXES FOR CANCER TREATMENT AND IMAGING Sciencons AS (NO) 2023-07-27 WO disclosed
WO-1992004336-A1 INTERMEDIATES FOR CHELATING AGENTS WITH PREFIXED SYMMETRY AND PROCESS FOR THEIR PREPARATION BRACCO INDUSTRIA CHIMICA S.P.A. (IT) 1992-03-19 WO disclosed
EP-0232751-B1 1-SUBSTITUTED-4,7,10-TRISCARBOXYMETHYL-1,4,7,10-TETRAAZACYCLODODECANE AND ANALOGS E.R. Squibb & Sons, Inc. (US) 1991-09-11 EP disclosed
US-4885363-A RADIOPHARMACEUTICAL IMAGING; MEDICAL DIAGNOSIS E. R. SQUIBB & SONS, INC. (US) 1989-12-05 US disclosed
EP-0292689-A2 Substituted 1,4,7-triscarboxymethyl-1,4,7,10-tetraazacyclo-dodecane and analogs BRACCO INTERNATIONAL B.V. (NL) 1988-11-30 EP disclosed
EP-0255471-A1 1,4,7,10-Tetraazacyclododecane-derivatives SCHERING AKTIENGESELLSCHAFT (DE) 1988-02-03 EP disclosed
EP-0232751-A1 1-substituted-4,7,10-triscarboxymethyl-1,4,7,10-tetraazacyclododecane and analogs E.R. Squibb & Sons, Inc. (US) 1987-08-19 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260109765-A1 MULTI-SPECIFIC ANTIBODIES WITH AFFINITY FOR HUMAN A33 ANTIGEN AND DOTA METAL COMPLEX AND USES THEREOF F13A1, CA13, MICA SIGMAR1 3923/4885CXCR4 1812/4885MEN1 518/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.