Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.96 |
| ▸ | CXCR4 | P61073 | 10/20 | 0.67 |
| ▸ | MEN1 | O00255 | 2/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.67 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.67 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.67 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.67 |
| ▸ | CCR2 | P41597 | 1/20 | 0.67 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.67 |
| ▸ | BLM | P54132 | 1/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.67 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.66 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.66 |
| ▸ | TSHR | P16473 | 1/20 | 0.66 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.66 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.66 |
| ▸ | MC4R | P32245 | 1/20 | 0.57 |
| ▸ | DRD4 | P21917 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Piperazine SCHEMBL28115310 | 1.00 | SIGMAR1 (0.96) | SIGMAR1CXCR4MEN1KMT2ACHRM2 | |
| SCHEMBL7062479 | 1.00 | SIGMAR1 (0.96) | SIGMAR1CXCR4MEN1KMT2ACHRM2 | |
| Hydrochloric Acid SCHEMBL8034018 | 0.98 | SIGMAR1 (0.92) | SIGMAR1CXCR4MEN1KMT2ACHRM2 | |
| SCHEMBL9538814 | 0.98 | SIGMAR1 (0.92) | SIGMAR1CXCR4MEN1KMT2ACHRM2 | |
| Bromide SCHEMBL21961924 | 0.98 | SIGMAR1 (0.92) | SIGMAR1CXCR4MEN1KMT2ACHRM2 | |
| SCHEMBL6138636 | 0.98 | SIGMAR1 (1.00) | SIGMAR1CXCR4MEN1KMT2ACHRM2 | |
| SCHEMBL83548 | 0.98 | SIGMAR1 (1.00) | SIGMAR1CXCR4MEN1KMT2ACHRM2 | |
| SCHEMBL152631 | 0.98 | SIGMAR1 (1.00) | SIGMAR1CXCR4MEN1KMT2ACHRM2 | |
| SCHEMBL276363 | 0.98 | SIGMAR1 (1.00) | SIGMAR1CXCR4MEN1KMT2ACHRM2 | |
| Benzene SCHEMBL27761330 | 0.98 | SIGMAR1 (1.00) | SIGMAR1CXCR4MEN1KMT2ACHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025120059-A1 | COMPOUND FOR DISORDERS ASSOCIATED WITH EXCESS AND/OR ACCUMULATION OF IRON IONS | BRACCO IMAGING SPA (IT) | 2025-06-12 | — | — | WO | claimed |
| EP-4561995-B1 | 1,4-BIS-(2-HYDROXY-BENZYL)-1,4,7-TRIAZACYCLONONANE DERIVATIVES AND SIMILAR COMPOUNDS AS LIGANDS IN IRON(III) COMPLEXES FOR USE AS MRI CONTRAST AGENTS | BRACCO IMAGING SPA (IT) | 2026-05-27 | — | — | EP | disclosed |
| US-12358880-B2 | 1,4-bis-(2-hydroxy-benzyl)-1,4,7-triazacyclononane derivatives and similar compounds as ligands in iron(III) complexes for use as MRI contrast agents | BRACCO IMAGING S.P.A. (IT) | 2025-07-15 | — | — | US | disclosed |
| WO-2025120059-A1 | COMPOUND FOR DISORDERS ASSOCIATED WITH EXCESS AND/OR ACCUMULATION OF IRON IONS | BRACCO IMAGING SPA (IT) | 2025-06-12 | — | — | WO | disclosed |
| US-20250163007-A1 | 1,4-BIS-(2-HYDROXY-BENZYL)-1,4,7-TRIAZACYCLONONANE DERIVATIVES AND SIMILAR COMPOUNDS AS LIGANDS IN IRON(III) COMPLEXES FOR USE AS MRI CONTRAST AGENTS | BRACCO IMAGING S.P.A. (IT) | 2025-05-22 | — | — | US | disclosed |
| CN-119735561-A | Preparation method, purification method and derivative of mono-benzyl substituted triazacyclononane | 上海凌凯科技股份有限公司 | 2025-04-01 | — | — | CN | disclosed |
| CN-119343336-A | 1, 4-Bis- (2-hydroxy-benzyl) -1,4, 7-triazacyclononane derivatives and similar compounds as ligands in iron (III) complexes for use as MRI contrast agents | 伯拉考成像股份公司 | 2025-01-21 | — | — | CN | disclosed |
| US-11344635-B2 | Compounds for use as iron (III) MRI contrast agents containing anionic pendents and ancillary groups | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2022-05-31 | — | — | US | disclosed |
| US-11344635-B2 | Compounds for use as iron (III) MRI contrast agents containing anionic pendents and ancillary groups | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2022-05-31 | — | — | US | disclosed |
| CN-113646009-A | Compounds comprising anionic side groups and auxiliary groups for use as iron (III) MRI contrast agents | 纽约州立大学研究基金会 | 2021-11-12 | — | — | CN | disclosed |
| US-20130287685-A1 | HER2 BINDING PEPTIDES LABELED WITH ALUMINIUM-[18] FLUORIDE COMPLEXED BY NOTA | GE HEALTHCARE LIMITED (GB) | 2013-10-31 | — | — | US | disclosed |
| US-20130287685-A1 | HER2 BINDING PEPTIDES LABELED WITH ALUMINIUM-[18] FLUORIDE COMPLEXED BY NOTA | GE HEALTHCARE LIMITED (GB) | 2013-10-31 | — | — | US | disclosed |
| US-20130156851-A1 | LIPOMACROCYCLES AND USES THEREOF | AGAVE PHARMA, INCORPORATED | 2013-06-20 | — | — | US | disclosed |
| US-20130156851-A1 | LIPOMACROCYCLES AND USES THEREOF | AGAVE PHARMA, INCORPORATED | 2013-06-20 | — | — | US | disclosed |
| WO-2013060793-A1 | BIFUNCTIONAL LIGANDS FOR RADIOMETALS | Technische Universität München (DE) | 2013-05-02 | — | — | WO | disclosed |
| WO-2013060793-A1 | BIFUNCTIONAL LIGANDS FOR RADIOMETALS | Technische Universität München (DE) | 2013-05-02 | — | — | WO | disclosed |
| WO-2012087912-A1 | HER2 BINDING PEPTIDES LABELLED WITH A 18F - CONTAINING ORGANOSILICON COMPOUND | GE HEALTHCARE LIMITED (GB) | 2012-06-28 | — | — | WO | disclosed |
| WO-2012087908-A1 | HER2 BINDING PEPTIDES LABELED WITH ALUMINIUM-[18] FLUORIDE COMPLEXED BY NOTA | GE HEALTHCARE LIMITED (GB) | 2012-06-28 | — | — | WO | disclosed |
| US-7270683-B2 | A triazacyclononane compound, hydrogen peroxide as an oxidizing agent, a base, and ethylenediaminetetraacetic acid, ethylenediaminehydroxyethyltriacetic acid, or diethylenetriaminepentaacetic acid; improved bleaching ability, bright color tone, reduced hair damage and scalp irritation | KAO CORPORATION (JP) | 2007-09-18 | — | — | US | disclosed |
| US-7270683-B2 | A triazacyclononane compound, hydrogen peroxide as an oxidizing agent, a base, and ethylenediaminetetraacetic acid, ethylenediaminehydroxyethyltriacetic acid, or diethylenetriaminepentaacetic acid; improved bleaching ability, bright color tone, reduced hair damage and scalp irritation | KAO CORPORATION (JP) | 2007-09-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250163007-A1 | 1,4-BIS-(2-HYDROXY-BENZYL)-1,4,7-TRIAZACYCLONONANE DERIVATIVES AND SIMILAR COMPOUNDS AS LIGANDS IN IRON(III) COMPLEXES FOR USE AS MRI CONTRAST AGENTS | TFRC, FTH1, FECH | SIGMAR1 256/4885CXCR4 2343/4885MEN1 441/4885 |
| US-20130287685-A1 | HER2 BINDING PEPTIDES LABELED WITH ALUMINIUM-[18] FLUORIDE COMPLEXED BY NOTA | ERBB2, EGFR, ERBB3 | SIGMAR1 2965/4885CXCR4 1713/4885MEN1 210/4885 |
| US-12358880-B2 | 1,4-bis-(2-hydroxy-benzyl)-1,4,7-triazacyclononane derivatives and similar compounds as ligands in iron(III) complexes for use as MRI contrast agents | TFRC, FTH1, FECH | SIGMAR1 256/4885CXCR4 2343/4885MEN1 441/4885 |
| US-11344635-B2 | Compounds for use as iron (III) MRI contrast agents containing anionic pendents and ancillary groups | SLC40A1, TAC3, ABCB7 | SIGMAR1 1907/4885CXCR4 3633/4885MEN1 151/4885 |
| US-20130156851-A1 | LIPOMACROCYCLES AND USES THEREOF | LIPC, LIPA, LIPE | SIGMAR1 3061/4885CXCR4 373/4885MEN1 1689/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.