SCHEMBL27639201

SCHEMBL27639201

CCOP(OCC)OC(Br)c1ccccc1

nearest known ligand 0.35

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.35
POLB P06746 3/20 0.35
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
L3MBTL1 Q9Y468 2/20 0.34
TAAR1 Q96RJ0 4/20 0.33
LTA4H P09960 1/20 0.33
MMP8 P22894 1/20 0.33
HKDC1 Q2TB90 1/20 0.33
MAPT P10636 1/20 0.32
MAPK1 P28482 1/20 0.32
SCN4A P35499 2/20 0.32
CES2 O00748 1/20 0.31
CES1 P23141 1/20 0.31
TRPA1 O75762 1/20 0.31
HTR2A P28223 1/20 0.31
HRH1 P35367 1/20 0.31
ATM Q13315 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL719260 0.81 HTT (0.40) LMNAPOLBMEN1KMT2AL3MBTL1
SCHEMBL5953984 0.79 LTB4R (0.39) LMNAPOLBMEN1KMT2AL3MBTL1
Bromide SCHEMBL2510983 0.76 TAAR1 (0.36) LMNAPOLBTAAR1MMP8HKDC1
SCHEMBL7563457 0.74 L3MBTL1 (0.42) LMNAPOLBL3MBTL1TAAR1MMP8
SCHEMBL8362086 0.70 CES2 (0.44) LMNATAAR1MAPK1CES2CES1
SCHEMBL385592 0.70 LTA4H (0.43) LMNAL3MBTL1LTA4H
SCHEMBL2859747 0.70 CES2 (0.41) LMNAPOLBKMT2AMAPK1CES2
SCHEMBL443626 0.70 LTA4H (0.43) LMNAL3MBTL1LTA4H
SCHEMBL28368572 0.68 LMNA (0.40) LMNAPOLBMEN1KMT2AL3MBTL1
SCHEMBL11557684 0.68 LTA4H (0.42) LMNAL3MBTL1LTA4H

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102786453-A Chiral sulfoxide alkene ligand, preparation method and application thereof DALIAN CHEMICAL PHYSICS INST 2012-11-21 CN claimed
CN-104238268-B Sulfosalt class photo-acid agent based on triphenylethylene, preparation method and applications 同济大学 2017-12-26 CN disclosed
CN-102786453-A Chiral sulfoxide alkene ligand, preparation method and application thereof DALIAN CHEMICAL PHYSICS INST 2012-11-21 CN disclosed
CN-1748183-A Electrophotographic photoreceptor and charge-transporting material for electrophotographic photoreceptor TAKASAGO PERFUMERY CO LTD (JP) 2006-03-15 CN disclosed