Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 3/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CHKA | P35790 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2098511 | 0.80 | CCR3 (0.42) | CCR3SLC6A2SLC6A4CA12CA1 | |
| SCHEMBL2098513 | 0.80 | CCR3 (0.42) | CCR3SLC6A2SLC6A4CA12CA1 | |
| SCHEMBL27665945 | 0.69 | EPHX2 (0.38) | CHRM1ALK | |
| SCHEMBL27645196 | 0.68 | DRD2 (0.41) | CCR3SLC6A2SLC6A4ALDH1A1KDM4E | |
| SCHEMBL27666154 | 0.65 | KCNH2 (0.54) | ALDH1A1KDM4ESMN1; SMN2CYP3A4CHRM1 | |
| SCHEMBL2092573 | 0.64 | ALDH1A1 (0.43) | SLC6A2SLC6A4CA12CA1CA2 | |
| SCHEMBL2092569 | 0.64 | RPS6KB1 (0.46) | CCR3SLC6A2SLC6A4CA12CA1 | |
| SCHEMBL27666019 | 0.63 | CHRM4 (0.50) | PKMALOX15CASP1HSD17B10ALDH1A1 | |
| SCHEMBL27666016 | 0.62 | ADRB2 (0.47) | SLC6A2SLC6A4KDM4EKCNH2HRH3 | |
| SCHEMBL27644442 | 0.62 | SLC6A2 (0.40) | CCR3SLC6A2SLC6A4ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100497345-C | 2, 3-dihydro-6-nitroimidazolo [2,1-b] oxazole compounds for the treatment of tuberculosis | OTSUKA PHARMA CO LTD (JP) | 2009-06-10 | — | — | CN | disclosed |
| CN-1878777-A | 2,3-dihydro-6-nitroimidazo (2,1-b) oxazole compounds for the treatment of tuberculosis | OTSUKA PHARMA CO LTD (JP) | 2006-12-13 | — | — | CN | disclosed |