Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20473351 | 0.80 | MEN1 (0.39) | ALDH1A1MEN1KMT2ACYP2C9CYP2C19 | |
| SCHEMBL15372490 | 0.78 | MEN1 (0.38) | ALDH1A1MEN1KMT2ACYP2C9CYP2C19 | |
| SCHEMBL118153 | 0.78 | MEN1 (0.38) | ALDH1A1MEN1KMT2AEPHX1CYP2C9 | |
| SCHEMBL3191405 | 0.77 | — | — | |
| SCHEMBL15360992 | 0.75 | POLB (0.36) | ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL4821811 | 0.75 | MEN1 (0.36) | ALDH1A1MEN1KMT2AEPHX1 | |
| SCHEMBL5729318 | 0.73 | FFAR3 (0.35) | ALDH1A1MEN1KMT2ACYP2C9CYP2C19 | |
| SCHEMBL19405340 | 0.72 | EPHX1 (0.43) | ALDH1A1MEN1KMT2AEPHX1LMNA | |
| SCHEMBL1616851 | 0.71 | CCR2 (0.35) | ALDH1A1MEN1KMT2AEPHX1 | |
| SCHEMBL2352621 | 0.71 | ALDH1A1 (0.38) | ALDH1A1MEN1KMT2ACYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11059783-B2 | Pyridinyl cyclohexanecarboxamide cooling compounds | GIVAUDAN S.A. (CH) | 2021-07-13 | — | — | US | disclosed |
| US-20190194134-A1 | PYRIDINYL CYCLOHEXANECARBOXAMIDE COOLING COMPOUNDS | GIVAUDAN S.A. (CH) | 2019-06-27 | — | — | US | disclosed |
| US-10221136-B2 | Pyridinyl cyclohexanecarboxamide cooling compounds | Givaudan, S.A. (CH) | 2019-03-05 | — | — | US | disclosed |
| US-20170008845-A1 | PYRIDINYL CYCLOHEXANECARBOXAMIDE COOLING COMPOUNDS | GIVAUDAN SA (CH) | 2017-01-12 | — | — | US | disclosed |
| US-9452982-B2 | Pyridinyl cyclohexanecarboxamide cooling compounds | Givaudan, S.A. (CH) | 2016-09-27 | — | — | US | disclosed |
| EP-1685093-B1 | N-SUBSTITUTED P-MENTHANE CARBOSAMIDED | GIVAUDAN SA (CH) | 2010-04-14 | — | — | EP | disclosed |
| US-20100035938-A1 | Cooling Compounds | GIVAUDAN SA (CH) | 2010-02-11 | — | — | US | disclosed |
| US-20090105237-A1 | Cooling compounds | GIVAUDAN SA (CH) | 2009-04-23 | — | — | US | disclosed |
| EP-1917074-A1 | COOLING COMPOUNDS | Givaudan SA (CH) | 2008-05-07 | — | — | EP | disclosed |
| EP-1885327-A1 | COOLING COMPOUNDS | Givaudan SA (CH) | 2008-02-13 | — | — | EP | disclosed |
| WO-2007019719-A1 | COOLING COMPOUNDS | GIVAUDAN SA (CH) | 2007-02-22 | — | — | WO | disclosed |
| WO-2006125334-A1 | COOLING COMPOUNDS | GIVAUDAN SA (CH) | 2006-11-30 | — | — | WO | disclosed |
| EP-1685093-A1 | N-SUBSTITUTED P-MENTHANE CARBOSAMIDED | Givaudan SA (CH) | 2006-08-02 | — | — | EP | disclosed |
| WO-2005049553-A1 | N-SUBSTITUTED P-MENTHANE CARBOSAMIDED | GIVAUDAN SA (CH) | 2005-06-02 | — | — | WO | disclosed |
| EP-1311158-B1 | COMPOSITION HAVING INSECT REPELLENT CHARACTERISTICS | GIVAUDAN SA (CH) | 2004-08-11 | — | — | EP | disclosed |
| US-20040028714-A1 | Composition having insect repellent characteristics | GIVAUDAN SA (CH) | 2004-02-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11059783-B2 | Pyridinyl cyclohexanecarboxamide cooling compounds | CBR3, TAS2R31, CTRB2 | ALDH1A1 1675/4885MEN1 1266/4885KMT2A 807/4885 |
| US-20170008845-A1 | PYRIDINYL CYCLOHEXANECARBOXAMIDE COOLING COMPOUNDS | CBR3, CTRB2, TAS2R31 | ALDH1A1 1603/4885MEN1 1336/4885KMT2A 872/4885 |
| US-20090105237-A1 | Cooling compounds | NR1H2, NR1H3, NR1H4 | ALDH1A1 506/4885MEN1 4311/4885KMT2A 2377/4885 |
| US-10221136-B2 | Pyridinyl cyclohexanecarboxamide cooling compounds | CBR3, CTRB2, TAS2R31 | ALDH1A1 1603/4885MEN1 1336/4885KMT2A 872/4885 |
| US-20100035938-A1 | Cooling Compounds | EBP, HRH1, TAS2R42 | ALDH1A1 945/4885MEN1 882/4885KMT2A 1969/4885 |
| US-20190194134-A1 | PYRIDINYL CYCLOHEXANECARBOXAMIDE COOLING COMPOUNDS | CBR3, TAS2R31, CTRB2 | ALDH1A1 1675/4885MEN1 1266/4885KMT2A 807/4885 |
| US-20040028714-A1 | Composition having insect repellent characteristics | SUV39H1, PNMT, SUV39H2 | ALDH1A1 1790/4885MEN1 142/4885KMT2A 305/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.