Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4196047 | 0.84 | — | — | |
| SCHEMBL4821811 | 0.83 | MEN1 (0.36) | MEN1ALDH1A1KMT2AEPHX1ALOX5 | |
| SCHEMBL20473351 | 0.80 | MEN1 (0.39) | MEN1ALDH1A1KMT2ACYP2C9CYP2C19 | |
| SCHEMBL23870287 | 0.79 | EPHX1 (0.31) | ALDH1A1KMT2AEPHX1 | |
| SCHEMBL19280369 | 0.79 | EPHX1 (0.31) | KMT2AEPHX1 | |
| SCHEMBL464807 | 0.79 | CYP1A2 (0.42) | MEN1ALDH1A1KMT2AEPHX1 | |
| SCHEMBL15372490 | 0.78 | MEN1 (0.38) | MEN1ALDH1A1KMT2ACYP2C9CYP2C19 | |
| SCHEMBL2764583 | 0.78 | ALDH1A1 (0.42) | MEN1ALDH1A1KMT2AEPHX1CYP2C9 | |
| SCHEMBL572320 | 0.77 | ALDH1A1 (0.34) | ALDH1A1EPHX1CYP2C19 | |
| SCHEMBL8958407 | 0.76 | ALDH1A1 (0.33) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 957 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250288583-A1 | Treatment of Mucus Hypersecretion | ALTA RESEARCH, LLC | 2025-09-18 | — | — | US | claimed |
| CN-120129464-A | Flavonoid compound and application thereof | 弗门尼舍有限公司 | 2025-06-10 | — | — | CN | claimed |
| CN-114555594-B | Substituted azacycles as TRMP modulators | 奇华顿股份有限公司 | 2025-03-18 | — | — | CN | claimed |
| CN-118984825-A | Novel cooling agent and preparation containing same | 西姆莱斯股份公司 | 2024-11-19 | — | — | CN | claimed |
| EP-4144230-B1 | CHILLED POUCH MATERIAL FOR NICOTINE POUCH | JT INT SA (CH) | 2024-08-07 | — | — | EP | claimed |
| US-20240197604-A1 | COMPOUNDS WITH COOLING SENSATION PROPERTIES | GIVAUDAN SA (CH) | 2024-06-20 | — | — | US | claimed |
| US-20240139087-A1 | ORGANIC COMPOUNDS AS TRPM8 ACTIVATORS | GIVAUDAN SA (CH) | 2024-05-02 | — | — | US | claimed |
| US-20240132487-A1 | SUBSTITUTED AZACYLES AS TRMP8 MODULATORS | GIVAUDAN SA (CH) | 2024-04-25 | — | — | US | claimed |
| EP-4326711-A1 | COMPOUNDS WITH COOLING SENSATION PROPERTIES | Givaudan SA (CH) | 2024-02-28 | — | — | EP | claimed |
| CN-117479843-A | Composition for enhancing cooling effect | 弗门尼舍公司 | 2024-01-30 | — | — | CN | claimed |
| US-20080311232-A1 | Cooling Compounds | GIVAUDAN, SA (CH) | 2008-12-18 | — | — | US | claimed |
| US-20080300314-A1 | Cooling Compounds | GIVAUDAN SA (CH) | 2008-12-04 | — | — | US | claimed |
| US-20080253974-A1 | 4-methoxy-N-phenyl-N-[2-(pyridin-2-yl)ethyl]benz(enesulfon)amide and a second cooling agent, such as menthol or a derivative; similar cooling intensity to N-ethyl p-menthanecarboxamide (WS-3); ingestible or topical | GIVAUDAN S.A. (CH) | 2008-10-16 | — | — | US | claimed |
| US-7414152-B2 | e. g. N-(4-cyanomethylphenyl) p-menthanecarboxamide; cooling agent in cosmetics and food industries; with additional cooling compound such as menthol, menthone, isopulegol | GIVAUDAN, SA (CH) | 2008-08-19 | — | — | US | claimed |
| EP-1014805-B1 | CHEWING GUM CONTAINING PHYSIOLOGICAL COOLING AGENTS | WRIGLEY W M JUN CO (US) | 2008-08-13 | — | — | EP | claimed |
| WO-2007126686-A2 | ABSORBENT ARTICLES WITH FEEDBACK SIGNAL UPON URINATION | THE PROCTER & GAMBLE COMPANY (US) | 2007-11-08 | — | — | WO | claimed |
| WO-2006127738-A9 | COMPRESSIBLE CHEWING GUMS FOR DELIVERY OF ACTIVES | CADBURY ADAMS USA LLC (US) | 2007-05-31 | — | — | WO | claimed |
| WO-2006127738-A2 | COMPRESSIBLE CHEWING GUMS FOR DELIVERY OF ACTIVES | CADBURY ADAMS USA LLC (US) | 2006-11-30 | — | — | WO | claimed |
| WO-2006127740-A2 | INDICIA-BEARING PACKAGE FOR DELIVERY SYSTEMS FOR MANAGING RELEASE OF SWEETENERS, SENSATES, FUNCTIONAL INGREDIENTS, FOOD ACIDS AND FLAVORS IN A COMPRESSIBLE GUM SYSTEM | CADBURY ADAMS USA LLC (US) | 2006-11-30 | — | — | WO | claimed |
| EP-0971676-B1 | DENTURE ADHESIVE COMPOSITIONS | PROCTER & GAMBLE (US) | 2004-12-22 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240132487-A1 | SUBSTITUTED AZACYLES AS TRMP8 MODULATORS | TRPM8, TRPM7, TRPM5 | MEN1 3357/4885ALDH1A1 871/4885KMT2A 741/4885 |
| US-20080300314-A1 | Cooling Compounds | TAS2R42, TAS2R4, TAS2R41 | MEN1 1791/4885ALDH1A1 2910/4885KMT2A 3567/4885 |
| US-20080311232-A1 | Cooling Compounds | MAL2, NCOR2, NCOA2 | MEN1 1810/4885ALDH1A1 2477/4885KMT2A 2201/4885 |
| US-20240197604-A1 | COMPOUNDS WITH COOLING SENSATION PROPERTIES | TRPM8, TRPM4, TRPM7 | MEN1 1703/4885ALDH1A1 2277/4885KMT2A 3610/4885 |
| US-20250288583-A1 | Treatment of Mucus Hypersecretion | TRPM8, GPR18, OPRL1 | MEN1 3414/4885ALDH1A1 4313/4885KMT2A 4405/4885 |
| US-20080253974-A1 | 4-methoxy-N-phenyl-N-[2-(pyridin-2-yl)ethyl]benz(enesulfon)amide and a second cooling agent, such as menthol or a derivative; similar cooling intensity to N-ethyl p-menthanecarboxamide (WS-3); ingestible or topical | CBR3, TRPM6, TRPV3 | MEN1 1766/4885ALDH1A1 3460/4885KMT2A 3236/4885 |
| US-20240139087-A1 | ORGANIC COMPOUNDS AS TRPM8 ACTIVATORS | TRPM8, TRPM7, TRPM4 | MEN1 1788/4885ALDH1A1 1334/4885KMT2A 2601/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.