Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MC5R | P33032 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | HTR1B | P28222 | 1/20 | 0.36 |
| ▸ | CCR4 | P51679 | 1/20 | 0.36 |
| ▸ | CCR5 | P51681 | 1/20 | 0.36 |
| ▸ | PDCD1LG2 | Q9BQ51 | 1/20 | 0.36 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MC1R | Q01726 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4153142 | 0.83 | IFNAR1 (0.45) | PTGS2GAA | |
| SCHEMBL28948705 | 0.80 | PTGS2 (0.42) | ALDH1A1PTGS2GPR84 | |
| SCHEMBL2769756 | 0.79 | MEN1 (0.40) | ALDH1A1MC5RMAPK1MEN1KMT2A | |
| SCHEMBL3626833 | 0.77 | MC5R (0.57) | MC5RMAPK1MEN1KMT2AHTR1B | |
| SCHEMBL16324650 | 0.75 | GPR84 (0.43) | ALDH1A1MC5RMAPK1MEN1KMT2A | |
| SCHEMBL28611445 | 0.73 | L3MBTL1 (0.41) | ALDH1A1PTGS2 | |
| SCHEMBL2769421 | 0.73 | HTR2A (0.50) | ALDH1A1PTGS2 | |
| SCHEMBL4339469 | 0.73 | L3MBTL1 (0.41) | ALDH1A1PTGS2 | |
| SCHEMBL7904045 | 0.73 | HTR2A (0.50) | ALDH1A1MEN1KMT2ASMN1; SMN2HTR1B | |
| SCHEMBL15352016 | 0.73 | L3MBTL1 (0.41) | ALDH1A1MEN1KMT2APTGS2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100534983-C | Cyclic amine derivatives, processes for their preparation, and pharmaceutical compositions containing them | GLAXO GROUP LTD (GB) | 2009-09-02 | — | — | CN | disclosed |
| CN-1819995-A | Cyclic amine derivatives, processes for their preparation, and pharmaceutical compositions containing them | GLAXO GROUP LTD (GB) | 2006-08-16 | — | — | CN | disclosed |