Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | MMP3 | P08254 | 1/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.33 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | PTPRC | P08575 | 1/20 | 0.30 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3244749 | 0.81 | HTT (0.44) | ENPP2KDM4ETDP1MMP3ABCB1 | |
| SCHEMBL8529341 | 0.76 | PTPRC (0.38) | ENPP2KDM4ETDP1MMP3FFAR1 | |
| SCHEMBL8746026 | 0.76 | ENPP2 (0.38) | ENPP2KDM4ETDP1MMP3FFAR1 | |
| SCHEMBL8526639 | 0.76 | ENPP2 (0.38) | ENPP2KDM4ETDP1MMP3FFAR1 | |
| SCHEMBL8528308 | 0.76 | TRPV4 (0.39) | ENPP2KDM4ETDP1MMP3FFAR1 | |
| SCHEMBL2126396 | 0.76 | ENPP2 (0.38) | ENPP2KDM4ETDP1MMP3ABCB1 | |
| SCHEMBL4712067 | 0.76 | SKP2 (0.52) | ENPP2KDM4ETDP1MMP3L3MBTL1 | |
| SCHEMBL7200049 | 0.76 | ENPP2 (0.38) | ENPP2KDM4ETDP1MMP3HTT | |
| SCHEMBL30354620 | 0.76 | PTPRC (0.41) | ENPP2KDM4ETDP1MMP3ABCB1 | |
| SCHEMBL25786460 | 0.76 | TSHR (0.43) | ENPP2KDM4ETDP1MMP3TRPV4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1956971-A | Novel fused heterocycles and application thereof | ASTRAZENECA AB (SE) | 2007-05-02 | — | — | CN | disclosed |