SCHEMBL8529341

SCHEMBL8529341

N#CCc1ccc(S)c(Br)c1

nearest known ligand 0.38

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
PTPRC P08575 1/20 0.38
PTPN1 P18031 1/20 0.38
ENPP2 Q13822 1/20 0.38
KDM4E B2RXH2 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
MMP3 P08254 1/20 0.36
CSNK2A1 P68400 4/20 0.33
FFAR1 O14842 1/20 0.32
CYP1A1 P04798 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP1B1 Q16678 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7198498 0.81 ENPP2 (0.41) PTPRCPTPN1ENPP2KDM4ETDP1
SCHEMBL8526639 0.76 ENPP2 (0.38) PTPRCPTPN1ENPP2KDM4ETDP1
SCHEMBL27660652 0.76 ENPP2 (0.38) PTPRCPTPN1ENPP2KDM4ETDP1
SCHEMBL8528308 0.76 TRPV4 (0.39) PTPRCPTPN1ENPP2KDM4ETDP1
SCHEMBL8746026 0.76 ENPP2 (0.38) PTPRCPTPN1ENPP2KDM4ETDP1
SCHEMBL4375333 0.76 ALOX15 (0.45) PTPRCPTPN1ENPP2KDM4ETDP1
SCHEMBL1006491 0.76 CSNK2A1 (0.42) PTPRCPTPN1ENPP2KDM4ETDP1
SCHEMBL333000 0.76 CYP1A2 (0.44) PTPRCPTPN1ENPP2KDM4ETDP1
SCHEMBL2125469 0.76 CSNK2A1 (0.42) PTPRCPTPN1ENPP2KDM4ETDP1
SCHEMBL3078182 0.76 PTPRC (0.38) PTPRCPTPN1ENPP2KDM4ETDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0692033-B1 ENHANCEMENT OF CHEMILUMINESCENT REACTIONS BRITISH TECH GROUP (GB) 1998-03-11 EP claimed
EP-0505198-B1 A method of enhancing a luminescent reaction, luminometric assay and kits for use in the same SANYO CHEMICAL IND LTD (JP) 1997-01-02 EP claimed
US-5512451-A MIXTURE OF A AROMATIC DIACYL CYCLIC HYDRAZIDE, PEROXIDASE CATALYST AND OXIDIZER BRITISH TECHNOLOGY GROUP LIMITED (GB) 1996-04-30 US claimed
EP-0692033-A1 ENHANCEMENT OF CHEMILUMINESCENT REACTIONS BTG INTERNATIONAL LIMITED (GB) 1996-01-17 EP claimed
WO-1994023060-A2 ENHANCEMENT OF CHEMILUMINESCENT REACTIONS BRITISH TECHNOLOGY GROUP LIMITED (GB) 1994-10-13 WO claimed
EP-0505198-A1 A method of enhancing a luminescent reaction, luminometric assay and kits for use in the same SANYO CHEMICAL INDUSTRIES, LTD. (JP) 1992-09-23 EP claimed
EP-0692033-B1 ENHANCEMENT OF CHEMILUMINESCENT REACTIONS BRITISH TECH GROUP (GB) 1998-03-11 EP disclosed
EP-0505198-B1 A method of enhancing a luminescent reaction, luminometric assay and kits for use in the same SANYO CHEMICAL IND LTD (JP) 1997-01-02 EP disclosed
US-5512451-A MIXTURE OF A AROMATIC DIACYL CYCLIC HYDRAZIDE, PEROXIDASE CATALYST AND OXIDIZER BRITISH TECHNOLOGY GROUP LIMITED (GB) 1996-04-30 US disclosed
EP-0692033-A1 ENHANCEMENT OF CHEMILUMINESCENT REACTIONS BTG INTERNATIONAL LIMITED (GB) 1996-01-17 EP disclosed
US-5424194-A Chemiluminescence SANYO CHEMICAL INDUSTRIES, LTD. (JP) 1995-06-13 US disclosed
WO-1994023060-A2 ENHANCEMENT OF CHEMILUMINESCENT REACTIONS BRITISH TECHNOLOGY GROUP LIMITED (GB) 1994-10-13 WO disclosed
EP-0505198-A1 A method of enhancing a luminescent reaction, luminometric assay and kits for use in the same SANYO CHEMICAL INDUSTRIES, LTD. (JP) 1992-09-23 EP disclosed