Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.51 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.51 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27644453 | 0.88 | SIGMAR1 (0.47) | MEN1ALDH1A1KMT2AADRA1DADRA1A | |
| SCHEMBL28761481 | 0.85 | HRH3 (0.43) | MEN1ALDH1A1KMT2AADRA1DADRA1A | |
| SCHEMBL27644980 | 0.81 | CTSS (0.42) | DRD2 | |
| SCHEMBL27665936 | 0.79 | HRH3 (0.46) | ALDH1A1ADRA1AADRA1BDRD2SIGMAR1 | |
| SCHEMBL27666169 | 0.78 | HRH3 (0.47) | ADRA1AADRA1BHTR1ADRD2SIGMAR1 | |
| SCHEMBL5013459 | 0.78 | MEN1 (0.52) | MEN1ALDH1A1KMT2AADRA1DADRA1A | |
| SCHEMBL27645120 | 0.78 | HRH3 (0.47) | ADRA1AADRA1BHTR1ADRD2SIGMAR1 | |
| SCHEMBL27645136 | 0.78 | HRH3 (0.47) | ADRA1AADRA1BHTR1ADRD2SIGMAR1 | |
| SCHEMBL28758331 | 0.77 | DRD4 (0.45) | MEN1ALDH1A1KMT2ADRD2SIGMAR1 | |
| SCHEMBL27644481 | 0.77 | ALDH1A1 (0.52) | MEN1ALDH1A1KMT2AHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100497345-C | 2, 3-dihydro-6-nitroimidazolo [2,1-b] oxazole compounds for the treatment of tuberculosis | OTSUKA PHARMA CO LTD (JP) | 2009-06-10 | — | — | CN | disclosed |
| CN-1878777-A | 2,3-dihydro-6-nitroimidazo (2,1-b) oxazole compounds for the treatment of tuberculosis | OTSUKA PHARMA CO LTD (JP) | 2006-12-13 | — | — | CN | disclosed |