Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.49 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.49 |
| ▸ | HTR1A | P08908 | 3/20 | 0.48 |
| ▸ | DRD2 | P14416 | 2/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | CASP4 | P49662 | 1/20 | 0.44 |
| ▸ | CASP5 | P51878 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5015080 | 0.77 | DRD2 (0.41) | MEN1ALDH1A1KMT2ADRD2 | |
| SCHEMBL5016133 | 0.77 | KMT2A (0.51) | MEN1ALDH1A1KMT2ACASP1BCHE | |
| SCHEMBL5011693 | 0.73 | ADRA1A (0.45) | ALDH1A1CYP2C9ADRA1DADRA1AADRA1B | |
| SCHEMBL8544808 | 0.73 | MEN1 (0.51) | MEN1ALDH1A1KMT2ACYP2C9ADRA1D | |
| Hydrochloric Acid SCHEMBL8591257 | 0.73 | MEN1 (0.51) | MEN1ALDH1A1KMT2ACYP2C9ADRA1D | |
| Hydrochloric Acid SCHEMBL6017322 | 0.72 | CYP2C9 (0.50) | MEN1ALDH1A1KMT2ACYP2C9ADRA1D | |
| SCHEMBL8687612 | 0.71 | HTR6 (0.61) | MEN1ALDH1A1KMT2ACYP2C9ADRA1D | |
| Hydrochloric Acid SCHEMBL9212305 | 0.71 | CYP2C9 (0.49) | MEN1ALDH1A1KMT2ACYP2C9ADRA1D | |
| SCHEMBL5011767 | 0.71 | HRH3 (0.45) | CYP2C9ADRA1DADRA1AADRA1BHTR1A | |
| SCHEMBL8549877 | 0.71 | HTR1A (0.54) | MEN1ALDH1A1KMT2ACYP2C9ADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1678185-B1 | 2,3-DIHYDRO-6-NITROIMIDAZO [2,1-B] OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMA CO LTD (JP) | 2008-10-08 | — | — | EP | disclosed |