Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 9/20 | 0.45 |
| ▸ | DRD2 | P14416 | 8/20 | 0.45 |
| ▸ | DRD3 | P35462 | 6/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NCF1 | P14598 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27666274 | 0.82 | MAPT (0.41) | L3MBTL1MAPTNPSR1TDP1MEN1 | |
| SCHEMBL27666126 | 0.79 | ALDH1A1 (0.46) | DRD4DRD2DRD3MAPTTDP1 | |
| SCHEMBL5015080 | 0.78 | DRD2 (0.41) | DRD4DRD2DRD3SIGMAR1L3MBTL1 | |
| SCHEMBL5015079 | 0.78 | DRD2 (0.41) | DRD4DRD2DRD3SIGMAR1L3MBTL1 | |
| SCHEMBL27666286 | 0.77 | MEN1 (0.54) | DRD2SIGMAR1MAPTNPSR1MEN1 | |
| SCHEMBL27644481 | 0.77 | ALDH1A1 (0.52) | DRD4DRD3TDP1MEN1RAB9A | |
| SCHEMBL27645280 | 0.75 | HRH1 (0.38) | — | |
| SCHEMBL27666383 | 0.73 | GNRHR (0.43) | DRD4DRD2DRD3NPSR1TDP1 | |
| SCHEMBL558603 | 0.72 | SMN1; SMN2 (0.43) | L3MBTL1MAPTTDP1MEN1NPC1 | |
| SCHEMBL27644453 | 0.71 | SIGMAR1 (0.47) | DRD2SIGMAR1MAPTTDP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100497345-C | 2, 3-dihydro-6-nitroimidazolo [2,1-b] oxazole compounds for the treatment of tuberculosis | OTSUKA PHARMA CO LTD (JP) | 2009-06-10 | — | — | CN | disclosed |
| CN-1878777-A | 2,3-dihydro-6-nitroimidazo (2,1-b) oxazole compounds for the treatment of tuberculosis | OTSUKA PHARMA CO LTD (JP) | 2006-12-13 | — | — | CN | disclosed |