Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.37 |
| ▸ | SUCNR1 | Q9BXA5 | 2/20 | 0.36 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.35 |
| ▸ | SRC | P12931 | 1/20 | 0.35 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.35 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.35 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 2/20 | 0.35 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.34 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.34 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.34 |
| ▸ | HNF4A | P41235 | 1/20 | 0.34 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10631889 | 0.77 | SLC6A4 (0.66) | SLC6A4SLC6A3PTGS2PTGS1TDP1 | |
| SCHEMBL6520358 | 0.75 | PTGS2 (0.40) | SLC6A4SLC6A3PTGS2PTGS1TDP1 | |
| SCHEMBL29283672 | 0.75 | HNF4A (0.46) | RECQLHNF4A | |
| SCHEMBL27927831 | 0.75 | MYC (0.42) | PTGS2PTGS1TDP1CYP2C19HNF4A | |
| SCHEMBL27466112 | 0.70 | ALDH1A1 (0.35) | PARP1 | |
| SCHEMBL29109421 | 0.69 | SLC6A3 (0.51) | SLC6A4SLC6A3FGFR1SRCFGFR2 | |
| SCHEMBL27669495 | 0.69 | MAPT (0.46) | HNF4A | |
| SCHEMBL496623 | 0.68 | SLC6A4 (0.64) | SLC6A4SLC6A3NR4A1CYP2C19LTB4R2 | |
| SCHEMBL28640320 | 0.68 | SLC6A3 (0.64) | SLC6A4SLC6A3PTGS2PTGS1TDP1 | |
| SCHEMBL11852148 | 0.68 | CYP3A4 (0.44) | TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-85101497-A | Process for the preparation of N-aryl-3-aryl-4, 5-dihydro-1H-pyrazole-1-carboxamides | — | 1986-07-16 | — | — | CN | disclosed |