Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Boric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Boric Acid SCHEMBL8764399 | 1.00 | LMNA (0.44) | LMNATSHRTDP1CA4FAHD1 | |
| Boric Acid SCHEMBL5024835 | 1.00 | LMNA (0.44) | LMNATSHRTDP1CA4FAHD1 | |
| Boric Acid SCHEMBL27838827 | 0.94 | LMNA (0.50) | LMNATSHRTDP1 | |
| Boric Acid SCHEMBL3464390 | 0.94 | LMNA (0.50) | LMNATSHRTDP1 | |
| Boric Acid SCHEMBL109148 | 0.94 | LMNA (0.50) | LMNATSHRTDP1 | |
| Boric Acid SCHEMBL5086901 | 0.94 | LMNA (0.50) | LMNATSHRTDP1 | |
| Boric Acid SCHEMBL27696095 | 0.94 | LMNA (0.50) | LMNATSHRTDP1 | |
| Potassium Ion SCHEMBL8071919 | 0.94 | — | — | |
| Boric Acid SCHEMBL1568305 | 0.94 | LMNA (0.50) | LMNATSHRTDP1 | |
| Boric Acid SCHEMBL9879761 | 0.89 | LMNA (0.44) | LMNATSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100335549-C | Rubber composition | SUMITOMO RUBBER IND (JP) | 2007-09-05 | — | — | CN | disclosed |