Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Boric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Boric Acid SCHEMBL109148 | 1.00 | LMNA (0.50) | LMNATSHRTDP1 | |
| Boric Acid SCHEMBL27696095 | 1.00 | LMNA (0.50) | LMNATSHRTDP1 | |
| Boric Acid SCHEMBL1568305 | 1.00 | LMNA (0.50) | LMNATSHRTDP1 | |
| Boric Acid SCHEMBL29124526 | 0.94 | LMNA (0.44) | LMNATSHRTDP1 | |
| Boric Acid SCHEMBL7887031 | 0.94 | LMNA (0.44) | LMNATSHRTDP1 | |
| Boric Acid SCHEMBL8461889 | 0.94 | LMNA (0.44) | LMNATSHRTDP1 | |
| Boric Acid SCHEMBL8764399 | 0.94 | LMNA (0.44) | LMNATSHRTDP1 | |
| Boric Acid SCHEMBL29114558 | 0.94 | LMNA (0.44) | LMNATSHRTDP1 | |
| Boric Acid SCHEMBL1523697 | 0.94 | LMNA (0.44) | LMNATSHRTDP1 | |
| Boric Acid SCHEMBL108232 | 0.94 | LMNA (0.44) | LMNATSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0676191-A2 | Antiperspirant deodorant compositions | HELENE CURTIS, INC. (US) | 1995-10-11 | — | — | EP | claimed |
| US-20080070838-A1 | Growth Factor Treatment for Asthma | UNIVERSITY OF SOUTHAMPTON (GB) | 2008-03-20 | — | — | US | disclosed |
| CN-101056649-A | Growth factor treatment for asthma | UNIV SOUTHAMPTON (GB) | 2007-10-17 | — | — | CN | disclosed |
| EP-1789138-A2 | GROWTH FACTOR TREATMENT FOR ASTHMA | UNIVERSITY OF SOUTHAMPTON (GB) | 2007-05-30 | — | — | EP | disclosed |
| WO-2006030241-A2 | GROWTH FACTOR TREATMENT FOR ASTHMA | UNIVERSITY OF SOUTHAMPTON (GB) | 2006-03-23 | — | — | WO | disclosed |