Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | AGTR1 | P30556 | 3/20 | 0.44 |
| ▸ | AGTR2 | P50052 | 3/20 | 0.44 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.44 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27678874 | 0.95 | APEX1 (0.54) | APEX1KDM4EGLAAGTR1AGTR2 | |
| SCHEMBL27697873 | 0.84 | APEX1 (0.51) | APEX1KDM4EPTGDR2 | |
| SCHEMBL9422759 | 0.79 | APEX1 (0.84) | APEX1KDM4EGLAAGTR1AGTR2 | |
| SCHEMBL1890982 | 0.77 | APEX1 (0.49) | APEX1KDM4EAGTR1AGTR2PTGDR2 | |
| SCHEMBL8931821 | 0.72 | APEX1 (0.47) | APEX1KDM4EGLAAGTR1AGTR2 | |
| SCHEMBL9531115 | 0.71 | APEX1 (0.65) | APEX1KDM4EGLAAGTR1AGTR2 | |
| SCHEMBL28238965 | 0.71 | HPGD (0.48) | KDM4ETLR7 | |
| SCHEMBL3825019 | 0.69 | TLR7 (0.42) | APEX1TLR7 | |
| SCHEMBL9125473 | 0.68 | AGTR1 (0.71) | AGTR1AGTR2TLR7 | |
| SCHEMBL9851085 | 0.68 | GLA (0.47) | APEX1KDM4EGLATLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101052397-A | 2-sulfanyl-benzoimidazol-1-yl-acetic acid derivatives | ACTELION PHARMACEUTICALS LTD (CH) | 2007-10-10 | — | — | CN | disclosed |