Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.39 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.39 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | CHKA | P35790 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.35 |
| ▸ | CHRNA6 | Q15825 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 4/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL594772 | 0.98 | FAAH (0.45) | FAAHTPSAB1TPSD1TPSG1CA2 | |
| SCHEMBL5239789 | 0.87 | FAAH (0.51) | FAAHTSHRALDH1A1KDM4EPOLB | |
| SCHEMBL27659208 | 0.82 | FAAH (0.48) | FAAHTSHRALDH1A1KDM4EPOLB | |
| SCHEMBL5239781 | 0.81 | FAAH (0.47) | FAAHTSHRALDH1A1KDM4EPOLB | |
| SCHEMBL13793796 | 0.79 | TSHR (0.61) | FAAHTSHRALDH1A1POLBHTT | |
| SCHEMBL21635185 | 0.79 | CA2 (0.39) | TPSAB1TPSD1TPSG1CA2CA12 | |
| SCHEMBL22115337 | 0.79 | GNAI3 (0.43) | CA2CA12CA1CA9CHRM5 | |
| N-(Ethoxycarbonyl)Piperazine SCHEMBL3889276 | 0.77 | TSHR (0.57) | CA2CA12CA1CA9TSHR | |
| SCHEMBL1679019 | 0.77 | TSHR (0.57) | CA2CA12CA1CA9TSHR | |
| N-(Ethoxycarbonyl)Piperazine SCHEMBL113765 | 0.77 | TSHR (0.57) | CA2CA12CA1CA9TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100567279-C | Alkylpiperazine-and alkylpiperazine-carboxylate derivatives, method for the production thereof and use thereof as FAAH enzyme inhibitors | SANOFI AVENTIS (FR) | 2009-12-09 | — | — | CN | disclosed |
| CN-1922162-A | Alkylpiperazine-and alkylpiperazine-carboxylate derivatives, method for the production thereof and use thereof as FAAH enzyme inhibitors | SANOFI AVENTIS (FR) | 2007-02-28 | — | — | CN | disclosed |