Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 6/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CDK9 | P50750 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27680696 | 0.81 | GAA (0.32) | TSHRNPSR1GAAALDH1A1 | |
| SCHEMBL27680699 | 0.77 | RAB9A (0.36) | TSHRGAARAB9ANPC1MAPT | |
| SCHEMBL27680695 | 0.75 | ALPG (0.40) | TSHRRAB9ANPC1 | |
| SCHEMBL27660667 | 0.75 | ALDH1A1 (0.43) | TSHRRAB9ANPC1MAPTALDH1A1 | |
| SCHEMBL27680813 | 0.74 | SMN1; SMN2 (0.44) | TSHRRAB9ANPC1CYP2C19 | |
| SCHEMBL4893983 | 0.73 | KDM4E (0.44) | TSHRNPSR1GAARAB9ANPC1 | |
| SCHEMBL27660858 | 0.71 | FPR2 (0.38) | TSHRRAB9ANPC1MAPTKMT2A | |
| SCHEMBL27961723 | 0.70 | ALDH1A1 (0.42) | TSHRRAB9ANPC1MAPTALDH1A1 | |
| SCHEMBL27680698 | 0.69 | HMOX1 (0.47) | MAPK1KDM4E | |
| SCHEMBL13316534 | 0.69 | RAB9A (0.42) | NPSR1GAARAB9ANPC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1989137-A | 3- '4- {6-substituted alkanoyl) pyridin-3-yl} -3-phenyl! -5- (1h-1, 2, 3-triazol-1-ylmethyl) -1, 3-oxazolidin-2-ones as antibacterial agents | ASTRAZENECA AB (SE) | 2007-06-27 | — | — | CN | disclosed |