Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27934254 | 0.86 | SLC6A1 (0.43) | ATM | |
| SCHEMBL27915636 | 0.86 | SLC6A1 (0.43) | ATM | |
| SCHEMBL27664282 | 0.86 | SLC6A1 (0.43) | ATM | |
| SCHEMBL27680770 | 0.84 | LMNA (0.31) | LMNAHSD17B10ATM | |
| SCHEMBL27694069 | 0.82 | KMT2A (0.37) | LMNAATM | |
| SCHEMBL27493732 | 0.82 | THRA (0.39) | LMNAHSD17B10ATM | |
| SCHEMBL27568926 | 0.82 | GABRA5 (0.34) | — | |
| Methyl Alcohol SCHEMBL27528171 | 0.81 | GABRA5 (0.33) | — | |
| Hydrochloric Acid SCHEMBL27691589 | 0.81 | GNAI3 (0.35) | — | |
| SCHEMBL27520063 | 0.79 | ALOX5 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108699032-B | Polycyclic TLR7/8 antagonists and their use in the treatment of immune disorders | 默克专利有限公司 | 2022-07-22 | — | — | CN | disclosed |
| CN-113603675-A | Polycyclic TLR7/8 antagonists and their use in the treatment of immune disorders | 默克专利有限公司 | 2021-11-05 | — | — | CN | disclosed |