Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | HRH2 | P25021 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 3/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | CASP3 | P42574 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27701258 | 0.81 | TSHR (0.35) | TSHRKMT2AGAAALDH1A1POLB | |
| SCHEMBL6736136 | 0.72 | TSHR (0.46) | TSHRKMT2AGAAALDH1A1POLB | |
| SCHEMBL7314915 | 0.69 | ALDH1A1 (0.35) | TSHRMEN1KMT2AGAAALDH1A1 | |
| SCHEMBL7068437 | 0.65 | LMNA (0.40) | TSHRMEN1KMT2AGAAALDH1A1 | |
| SCHEMBL2110264 | 0.63 | SIGMAR1 (0.42) | TSHRKMT2AGAAALDH1A1CYP3A4 | |
| SCHEMBL6129180 | 0.63 | ALDH1A1 (0.46) | TSHRKMT2ASMN1; SMN2GAAALDH1A1 | |
| SCHEMBL11556911 | 0.63 | LMNA (0.53) | MEN1KMT2AALDH1A1LMNANPC1 | |
| Hydrochloric Acid SCHEMBL7970534 | 0.62 | SIGMAR1 (0.41) | TSHRKMT2ASMN1; SMN2GAAALDH1A1 | |
| SCHEMBL11024710 | 0.61 | LMNA (0.46) | MEN1KMT2AALDH1A1LMNAKDM4E | |
| SCHEMBL4089646 | 0.60 | ALDH1A1 (0.43) | TSHRKMT2ASMN1; SMN2GAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101041636-B | Method for synthesizing heterocyclic ketenes amine condensation derivatives | CHINESE ACAD INST CHEMISTRY | 2010-05-12 | — | — | CN | disclosed |
| CN-101041636-A | Method for synthesizing heterocyclic ketenes amine condensation derivatives | CHINESE ACAD INST CHEMISTRY (CN) | 2007-09-26 | — | — | CN | disclosed |