Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | SCN1A | P35498 | 1/20 | 0.32 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.32 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.31 |
| ▸ | FBP1 | P09467 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.30 |
| ▸ | RAB9A | P51151 | 2/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2983284 | 0.77 | FFAR1 (0.41) | FFAR1FFAR4KMT2AHDAC1ESR1 | |
| SCHEMBL7535772 | 0.70 | FBP1 (0.47) | KMT2AALDH1A1MEN1FBP1NPC1 | |
| SCHEMBL2976681 | 0.70 | SIGMAR1 (0.45) | KMT2AMEN1HTT | |
| SCHEMBL18939227 | 0.69 | LMNA (0.46) | KMT2AALDH1A1MEN1NPC1RAB9A | |
| SCHEMBL27812591 | 0.68 | FFAR1 (0.51) | FFAR1FFAR4KMT2APOLBHDAC1 | |
| SCHEMBL2975777 | 0.68 | FBP1 (0.41) | KMT2AALDH1A1SCN1ASCN2ASCN3A | |
| Bromide SCHEMBL27812103 | 0.67 | FFAR1 (0.50) | FFAR1FFAR4KMT2APOLBHDAC1 | |
| SCHEMBL8145854 | 0.64 | ALDH1A1 (0.52) | FFAR1FFAR4KMT2APOLBHDAC1 | |
| Hydrochloric Acid SCHEMBL27988328 | 0.63 | ALDH1A1 (0.51) | FFAR1FFAR4KMT2APOLBHDAC1 | |
| SCHEMBL27873330 | 0.62 | FDPS (0.38) | POLBALDH1A1FBP1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101115749-B | Aminopyrimidine compounds and methods of use | AMGEN INC | 2011-06-22 | — | — | CN | disclosed |
| CN-101115749-A | Aminopyrimidine compounds and methods of use | AMGEN INC (US) | 2008-01-30 | — | — | CN | disclosed |