Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 5/20 | 0.58 |
| ▸ | ADRA1A | P35348 | 5/20 | 0.58 |
| ▸ | ADRA1B | P35368 | 5/20 | 0.58 |
| ▸ | HTR1A | P08908 | 2/20 | 0.58 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.56 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.50 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2769304 | 0.84 | ADRA1D (0.62) | ADRA1DADRA1AADRA1BHTR1ASIGMAR1 | |
| SCHEMBL2768032 | 0.83 | ADRA1D (0.61) | ADRA1DADRA1AADRA1BHTR1ASIGMAR1 | |
| SCHEMBL2767088 | 0.81 | HTR1A (0.51) | ADRA1DADRA1AADRA1BHTR1ASIGMAR1 | |
| SCHEMBL2766536 | 0.80 | OPRM1 (0.46) | HTR1ASLC6A4 | |
| SCHEMBL2768019 | 0.79 | SIGMAR1 (0.53) | HTR1ASIGMAR1SLC6A4 | |
| SCHEMBL13150788 | 0.77 | SIGMAR1 (0.88) | SIGMAR1 | |
| SCHEMBL2766150 | 0.77 | SIGMAR1 (0.72) | ADRA1DADRA1AADRA1BHTR1ASIGMAR1 | |
| SCHEMBL2767177 | 0.75 | MAPT (0.47) | HTR1ASIGMAR1 | |
| SCHEMBL3713046 | 0.74 | MAPT (0.59) | ADRA1DADRA1AADRA1BHTR1ASLC6A4 | |
| SCHEMBL2768386 | 0.74 | MAPT (0.49) | ADRA1DADRA1AADRA1BHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1627871-B1 | CYCLIC AMINOPHENYL SULFAMATE DERIVATIVE | ASKA PHARM CO LTD (JP) | 2010-04-14 | — | — | EP | disclosed |
| US-7449466-B2 | Cyclic aminophenyl sulfamate derivative | ASKA PHARMACEUTICAL CO., LTD. (JP) | 2008-11-11 | — | — | US | disclosed |
| US-20060189625-A1 | Cyclic aminophenyl sulfamate derivative | ASKA PHARMACEUTICAL CO., LTD. (JP) | 2006-08-24 | — | — | US | disclosed |
| EP-1627871-A1 | CYCLIC AMINOPHENYL SULFAMATE DERIVATIVE | Teikoku Hormone Mfg. Co., Ltd. (JP) | 2006-02-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060189625-A1 | Cyclic aminophenyl sulfamate derivative | SHBG, STS, ARSA | ADRA1D 2006/4885ADRA1A 2425/4885ADRA1B 1233/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.