Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | BACE1 | P56817 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | HRH1 | P35367 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10698243 | 0.89 | ALDH1A1 (0.53) | ALDH1A1LMNAPOLBKMT2AMEN1 | |
| SCHEMBL978103 | 0.88 | ALDH1A1 (0.66) | ALDH1A1LMNAPOLBKMT2AMEN1 | |
| SCHEMBL10729859 | 0.83 | ALDH1A1 (0.55) | ALDH1A1LMNAPOLBKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL10734488 | 0.81 | ALDH1A1 (0.53) | ALDH1A1LMNAPOLBKMT2AMEN1 | |
| SCHEMBL3333802 | 0.81 | MAOA (0.49) | ALDH1A1POLBACHEBACE1MAPK1 | |
| SCHEMBL22468374 | 0.80 | SIGMAR1 (0.60) | ALDH1A1POLBKMT2AMEN1HRH3 | |
| SCHEMBL159371 | 0.80 | SIGMAR1 (0.61) | ALDH1A1LMNAPOLBKMT2AACHE | |
| SCHEMBL7989530 | 0.79 | LMNA (0.83) | ALDH1A1LMNAPOLBKMT2AMEN1 | |
| SCHEMBL11356824 | 0.79 | LMNA (0.83) | ALDH1A1LMNAPOLBKMT2AMEN1 | |
| SCHEMBL1045922 | 0.79 | LMNA (0.83) | ALDH1A1LMNAPOLBKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101001851-B | Hydroxyamide compounds having activity as inhibitors of histone deacetylase (HDAC) | ASTELLAS PHARMA INC | 2011-04-20 | — | — | CN | disclosed |
| CN-101001851-A | Hydroxyamide compounds having activity as inhibitors of histone deacetylase (HDAC) | ASTELLAS PHARMA INC (JP) | 2007-07-18 | — | — | CN | disclosed |