Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP3 | P08254 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ACACB | O00763 | 2/20 | 0.39 |
| ▸ | ACACA | Q13085 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22651641 | 0.81 | ALDH1A1 (0.51) | MAPTHPGDSMN1; SMN2ALDH1A1MTNR1A | |
| SCHEMBL7749771 | 0.78 | MAPT (0.51) | MAPTHPGDSMN1; SMN2ALDH1A1MMP2 | |
| SCHEMBL12384285 | 0.78 | MTNR1A (0.58) | MAPTLMNAMTNR1AMTNR1BKMT2A | |
| SCHEMBL11780675 | 0.76 | ALDH1A1 (0.50) | MAPTHPGDSMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL7045834 | 0.76 | MAPT (0.54) | MAPTSMN1; SMN2LMNAALDH1A1MTNR1A | |
| SCHEMBL3717529 | 0.76 | LOXL2 (0.51) | LMNAMMP2MMP3GAATSHR | |
| SCHEMBL16379337 | 0.75 | ALDH1A1 (0.50) | LMNAALDH1A1 | |
| SCHEMBL14341658 | 0.74 | MAPT (0.47) | MAPTHPGDSMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL1808357 | 0.72 | TDP1 (0.44) | MAPTLMNAALDH1A1MTNR1AMTNR1B | |
| SCHEMBL5229538 | 0.71 | MAPT (0.53) | MAPTHPGDSMN1; SMN2ALDH1A1MTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101014580-B | Morpholine compound | MITSUBISHI PHARMA CORP | 2011-05-04 | — | — | CN | disclosed |
| CN-101014580-A | Morpholine compound | MITSUBISHI PHARMA CORP (JP) | 2007-08-08 | — | — | CN | disclosed |