Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCP | P55072 | 2/20 | 0.49 |
| ▸ | CFTR | P13569 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.46 |
| ▸ | MEN1 | O00255 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | MRE11 | P49959 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | NSD2 | O96028 | 1/20 | 0.40 |
| ▸ | ALPL | P05186 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ALPI | P09923 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4080677 | 0.78 | ALOX5 (0.70) | VCPCFTRKDM4EKMT2AMEN1 | |
| SCHEMBL9250823 | 0.74 | CDC25A (0.52) | VCPKDM4EKMT2AMEN1MAPT | |
| SCHEMBL14458516 | 0.73 | ALOX5 (0.72) | VCPCFTRKDM4EKMT2AMEN1 | |
| SCHEMBL4078495 | 0.73 | KDM4E (0.51) | VCPCFTRKDM4EKMT2AMEN1 | |
| SCHEMBL4074331 | 0.73 | KDM4E (0.48) | VCPCFTRKDM4EKMT2AMEN1 | |
| SCHEMBL3603836 | 0.71 | MAPT (0.59) | VCPCFTRKDM4EKMT2AMEN1 | |
| SCHEMBL12298086 | 0.70 | CFTR (0.64) | VCPCFTRKDM4EKMT2AMEN1 | |
| SCHEMBL23742654 | 0.70 | VCP (0.58) | VCPCFTRKDM4EKMT2AMEN1 | |
| SCHEMBL10660997 | 0.69 | KDM4E (0.46) | VCPCFTRKDM4EKMT2AMEN1 | |
| SCHEMBL8824039 | 0.69 | ITGB3 (0.58) | KDM4EKMT2AMEN1MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101098862-A | New 3-phenylpropionic acid derivatives and their use as ppar-gamma rezeptor liganden | ADAMED SP ZOO (PL) | 2008-01-02 | — | — | CN | disclosed |