SCHEMBL27698258

SCHEMBL27698258

CCOC(=O)Oc1ccncc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.47
NPSR1 Q6W5P4 1/20 0.46
HSD17B10 Q99714 1/20 0.46
ALDH1A1 P00352 2/20 0.45
MAPT P10636 2/20 0.45
KDM4E B2RXH2 1/20 0.45
MEN1 O00255 1/20 0.45
MMP2 P08253 1/20 0.43
MMP9 P14780 1/20 0.43
MMP8 P22894 1/20 0.43
MMP14 P50281 1/20 0.43
LMNA P02545 3/20 0.43
CYP1A2 P05177 2/20 0.43
CYP2C9 P11712 2/20 0.43
CYP2C19 P33261 2/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
CDC7 O00311 2/20 0.43
DBF4 Q9UBU7 2/20 0.43
NPC1 O15118 2/20 0.43
CYP3A4 P08684 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6451238 0.86 ALDH1A1 (0.55) KMT2AHSD17B10ALDH1A1MAPTKDM4E
SCHEMBL18727667 0.81 HSD17B10 (0.58) KMT2ANPSR1HSD17B10ALDH1A1KDM4E
SCHEMBL18917196 0.80 KMT2A (0.44) KMT2AHSD17B10ALDH1A1MAPTKDM4E
SCHEMBL1598705 0.80 LMNA (0.57) KMT2AALDH1A1MAPTKDM4EMEN1
SCHEMBL37520 0.80 MAPT (0.56) KMT2AHSD17B10ALDH1A1MAPTMEN1
SCHEMBL9453034 0.80 LMNA (0.59) KMT2AALDH1A1MAPTMEN1LMNA
SCHEMBL9521880 0.79 CCNC (0.58) KMT2ANPSR1ALDH1A1MAPTKDM4E
SCHEMBL6894576 0.78 GAA (0.51) KMT2AHSD17B10ALDH1A1KDM4EMEN1
SCHEMBL8536318 0.78 CA2 (0.55) KMT2AALDH1A1MAPTKDM4EMEN1
Hydrochloric Acid SCHEMBL9839090 0.78 CCNC (0.57) KMT2ANPSR1ALDH1A1MAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107312173-B polyimide precursor and use thereof 长兴材料工业股份有限公司 2019-12-17 CN disclosed
CN-103189376-B There is ketone group sultam and the diketo pyridine of weeding activity BAYER INTELLECTUAL PROPERTY GMBH (DE) 2016-02-24 CN disclosed
CN-103189376-A Herbicidally active ketosultams and diketopyridines BAYER IP GMBH 2013-07-03 CN disclosed
CN-101031299-A Thienopyridinone compounds and methods of treatment EPIX DELAWARE INC (US) 2007-09-05 CN disclosed