Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
| ▸ | MMP14 | P50281 | 1/20 | 0.38 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.38 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.36 |
| ▸ | CCNC | P24863 | 1/20 | 0.36 |
| ▸ | CDK8 | P49336 | 1/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.36 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27698258 | 0.80 | KMT2A (0.47) | KMT2AALDH1A1CA2MEN1MMP2 | |
| SCHEMBL9521880 | 0.78 | CCNC (0.58) | KMT2AALDH1A1MEN1POLBCCNC | |
| SCHEMBL6451238 | 0.77 | ALDH1A1 (0.55) | KMT2AALDH1A1CA2MEN1POLB | |
| Hydrochloric Acid SCHEMBL9839090 | 0.77 | CCNC (0.57) | KMT2AALDH1A1MEN1POLBCCNC | |
| SCHEMBL20322869 | 0.77 | GAA (0.53) | ALDH1A1POLBHSD17B10MAPTTSHR | |
| SCHEMBL27972799 | 0.76 | LMNA (0.47) | KMT2AALDH1A1MEN1POLBHCAR2 | |
| SCHEMBL19664385 | 0.75 | KMT2A (0.43) | KMT2AALDH1A1CA2MEN1POLB | |
| SCHEMBL185926 | 0.74 | HCAR2 (0.48) | KMT2AMEN1HCAR2HSD17B10LMNA | |
| SCHEMBL19664384 | 0.73 | KMT2A (0.45) | KMT2AALDH1A1CA2MEN1POLB | |
| SCHEMBL27805453 | 0.73 | HCAR2 (0.46) | KMT2AALDH1A1CA2L3MBTL1SOAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2807162-B1 | SUBSTITUTED PHENYLIMIDAZOPYRAZOLES AND USE THEREOF | Bayer Pharma AG (DE) | 2017-06-07 | — | — | EP | disclosed |