SCHEMBL3800751

SCHEMBL3800751

Cc1ccccc1S([N])(=O)=O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.43
ACHE P22303 1/20 0.43
RAPGEF4 Q8WZA2 1/20 0.42
ALDH1A1 P00352 3/20 0.41
KDM4E B2RXH2 3/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
TP53 P04637 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
HSD11B1 P28845 1/20 0.40
RXFP1 Q9HBX9 1/20 0.40
EDNRA P25101 1/20 0.40
HTR2A P28223 1/20 0.39
HTR2C P28335 1/20 0.39
MEN1 O00255 1/20 0.39
ESR1 P03372 1/20 0.39
GAA P10253 1/20 0.39
KMT2A Q03164 1/20 0.39
ESR2 Q92731 1/20 0.39
CTSG P08311 1/20 0.39
CMA1 P23946 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29468592 0.79 ALDH1A1 (0.55) TSHRACHERAPGEF4ALDH1A1KDM4E
SCHEMBL4533183 0.79 TSHR (0.47) TSHRACHERAPGEF4ALDH1A1KDM4E
SCHEMBL475089 0.79 ALDH1A1 (0.55) TSHRACHERAPGEF4ALDH1A1KDM4E
SCHEMBL28503918 0.78 HSD11B1 (0.42) TSHRACHERAPGEF4ALDH1A1KDM4E
SCHEMBL28278788 0.77 L3MBTL1 (0.50) TSHRACHERAPGEF4ALDH1A1KDM4E
SCHEMBL12307 0.77 L3MBTL1 (0.50) TSHRACHERAPGEF4ALDH1A1KDM4E
SCHEMBL79052 0.77 TSHR (0.45) TSHRACHERAPGEF4ALDH1A1KDM4E
Cyanide SCHEMBL27700014 0.76 L3MBTL1 (0.45) TSHRACHERAPGEF4ALDH1A1KDM4E
SCHEMBL5075646 0.75 TSHR (0.43) TSHRACHERAPGEF4ALDH1A1KDM4E
SCHEMBL305238 0.75 TSHR (0.43) TSHRACHERAPGEF4ALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9193747-B2 Organic electroluminescent device UDC IRELAND LIMITED (IE) 2015-11-24 US disclosed
US-20100171111-A1 ORGANIC ELECTROLUMINESCENT DEVICE FUJIFILM CORPORATION (JP) 2010-07-08 US disclosed
US-4624956-A Ulcer and gastric secretion inhibiting 4,5,6,7-tetrahydrothiazole[5,4-c]pyridine derivatives FARMITALIA CARLO ERBA (IT) 1986-11-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100171111-A1 ORGANIC ELECTROLUMINESCENT DEVICE NDUFS3, NDUFS2, NDUFS4 TSHR 3933/4885ACHE 1604/4885RAPGEF4 3159/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.