Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 9/20 | 0.48 |
| ▸ | AKR1C2 | P52895 | 8/20 | 0.48 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.48 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.48 |
| ▸ | AKR1C4 | P17516 | 2/20 | 0.48 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | MYC | P01106 | 1/20 | 0.41 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | PYGM | P11217 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23864713 | 0.81 | KDM4E (0.36) | AKR1C3AKR1C2AKR1B10AKR1B1AKR1C4 | |
| SCHEMBL23864317 | 0.79 | CASP3 (0.36) | AKR1C3AKR1C2KMT2AMEN1ALDH1A1 | |
| SCHEMBL23864289 | 0.76 | HIF1A (0.43) | KMT2AMEN1ALDH1A1KDM4EHPGD | |
| SCHEMBL24166924 | 0.74 | ALDH1A1 (0.42) | POLBKMT2AMEN1ALDH1A1ALOX15 | |
| SCHEMBL3860177 | 0.73 | HPGD (0.56) | AKR1C3AKR1C2AKR1B10AKR1B1AKR1C4 | |
| SCHEMBL17681587 | 0.73 | CA12 (0.47) | AKR1C3POLBKMT2AMEN1ALDH1A1 | |
| SCHEMBL23864607 | 0.72 | HPGD (0.49) | ALDH1A1KDM4EHPGD | |
| SCHEMBL23864419 | 0.71 | CRHBP (0.37) | KMT2AMEN1ALDH1A1KDM4EHPGD | |
| SCHEMBL23864250 | 0.71 | LOXL2 (0.39) | KMT2AALDH1A1L3MBTL1TSHR | |
| SCHEMBL4662625 | 0.71 | NPSR1 (0.49) | POLBKMT2AMEN1CREBBPALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101087601-A | Compounds for inhibiting copper-containing amine oxidases and uses thereof | GENMEDICA THERAPEUTICS SL (ES) | 2007-12-12 | — | — | CN | disclosed |