Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23864289 | 0.86 | HIF1A (0.43) | ALDH1A1KDM4EHPGDKMT2AMEN1 | |
| SCHEMBL23864713 | 0.83 | KDM4E (0.36) | ALDH1A1KDM4EHPGDKMT2AL3MBTL1 | |
| SCHEMBL27701150 | 0.79 | AKR1C3 (0.48) | ALDH1A1KDM4EHPGDKMT2AL3MBTL1 | |
| SCHEMBL23864607 | 0.75 | HPGD (0.49) | ALDH1A1KDM4EHPGDRAB9ANPC1 | |
| SCHEMBL23864250 | 0.74 | LOXL2 (0.39) | ALDH1A1KMT2AL3MBTL1RAB9ACYP2C19 | |
| SCHEMBL23864419 | 0.74 | CRHBP (0.37) | ALDH1A1KDM4EHPGDKMT2AL3MBTL1 | |
| SCHEMBL17134331 | 0.72 | CASP3 (0.39) | CASP3GFERSENP8SENP7SENP6 | |
| SCHEMBL17134332 | 0.72 | CASP3 (0.39) | CASP3GFERSENP8SENP7SENP6 | |
| SCHEMBL23864351 | 0.71 | POLB (0.43) | ALDH1A1HPGDLMNA | |
| SCHEMBL23864569 | 0.71 | LMNA (0.40) | ALDH1A1HPGDKMT2AL3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2968330-B1 | COMPOUNDS AND METHODS FOR INDUCING CHONDROGENESIS | SCRIPPS RESEARCH INST (US) | 2021-09-29 | — | — | EP | disclosed |