Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EED | O75530 | 1/20 | 0.35 |
| ▸ | RBBP4 | Q09028 | 1/20 | 0.35 |
| ▸ | SUZ12 | Q15022 | 1/20 | 0.35 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.35 |
| ▸ | AEBP2 | Q6ZN18 | 1/20 | 0.35 |
| ▸ | REV1 | Q9UBZ9 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27693406 | 0.91 | REV1 (0.35) | EEDRBBP4SUZ12EZH2AEBP2 | |
| SCHEMBL5449859 | 0.85 | EED (0.49) | EEDRBBP4SUZ12EZH2AEBP2 | |
| SCHEMBL5729820 | 0.83 | MAPT (0.38) | EEDRBBP4SUZ12EZH2AEBP2 | |
| SCHEMBL5439719 | 0.79 | REV1 (0.42) | EEDRBBP4SUZ12EZH2AEBP2 | |
| SCHEMBL5728106 | 0.77 | EED (0.31) | EEDRBBP4SUZ12EZH2AEBP2 | |
| SCHEMBL27712946 | 0.73 | ALDH1A1 (0.40) | EEDRBBP4SUZ12EZH2AEBP2 | |
| SCHEMBL5441982 | 0.68 | EED (0.50) | EEDRBBP4SUZ12EZH2AEBP2 | |
| SCHEMBL23412814 | 0.67 | KDM4E (0.50) | REV1RXFP1KDM4ELMNANPSR1 | |
| SCHEMBL578700 | 0.67 | EPHX1 (0.43) | NPC1RAB9AMAPT | |
| SCHEMBL14764299 | 0.65 | DDB1 (0.41) | KDM4EMAPTTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1694665-A2 | SUBSTITUTED THIOPHENES | AiCuris GmbH & Co. KG (DE) | 2006-08-30 | — | — | EP | disclosed |
| WO-2005063734-A2 | SUBSTITUTED THIOPHENES | AICURIS GMBH & CO. KG (DE) | 2005-07-14 | — | — | WO | disclosed |