Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | DDX3X | O00571 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | MITF | O75030 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5081573 | 0.81 | TSHR (0.47) | POLBDDX3XTDP1ALDH1A1CYP1A2 | |
| SCHEMBL27861590 | 0.81 | TSHR (0.47) | POLBDDX3XTDP1ALDH1A1CYP1A2 | |
| SCHEMBL277752 | 0.81 | LMNA (0.52) | LMNACES2CES1MAPK1POLB | |
| SCHEMBL3259212 | 0.81 | GPR35 (0.46) | LMNACES2CES1MAPK1TDP1 | |
| SCHEMBL27866291 | 0.80 | LMNA (0.44) | LMNACES2CES1MAPK1ALDH1A1 | |
| SCHEMBL8227998 | 0.80 | CES2 (0.45) | LMNACES2CES1MAPK1TDP1 | |
| SCHEMBL3069224 | 0.79 | ALDH1A1 (0.40) | POLBDDX3XTDP1ALDH1A1CYP1A2 | |
| SCHEMBL27936141 | 0.78 | ALDH1A1 (0.43) | LMNACES2CES1MAPK1POLB | |
| SCHEMBL5405432 | 0.75 | LMNA (0.49) | LMNACES2CES1MAPK1ALDH1A1 | |
| SCHEMBL787459 | 0.74 | ALDH1A1 (0.53) | LMNACES2CES1MAPK1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101410519-A | Metapneumovirus strains and their use in vaccine formulations and as vectors for expression of antigenic sequences and methods for propagating viruses | MEDIMMUNE VACCINES INC (US) | 2009-04-15 | — | — | CN | disclosed |
| CN-101098958-A | Metapneumovirus strains and their use in vaccine formulations and as vectors for expression of antigenic sequences | MEDIMMUNE VACCINES INC (US) | 2008-01-02 | — | — | CN | disclosed |