Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | CES2 | O00748 | 2/20 | 0.49 |
| ▸ | CES1 | P23141 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.39 |
| ▸ | CTSD | P07339 | 1/20 | 0.39 |
| ▸ | CASP6 | P55212 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3259212 | 0.88 | GPR35 (0.46) | LMNACES2CES1MAPK1ALDH1A1 | |
| SCHEMBL787459 | 0.81 | ALDH1A1 (0.53) | LMNACES2CES1MAPK1ALDH1A1 | |
| Carbamic Acid SCHEMBL25425926 | 0.81 | CTSD (0.50) | LMNACES2CES1MAPK1ALDH1A1 | |
| SCHEMBL27866291 | 0.78 | LMNA (0.44) | LMNACES2CES1MAPK1ALDH1A1 | |
| SCHEMBL8227998 | 0.78 | CES2 (0.45) | LMNACES2CES1MAPK1ALDH1A1 | |
| SCHEMBL8835492 | 0.78 | LMNA (0.38) | LMNACES2CES1MAPK1ALDH1A1 | |
| SCHEMBL9406620 | 0.77 | ALDH1A1 (0.48) | LMNACES2CES1MAPK1ALDH1A1 | |
| SCHEMBL28752436 | 0.77 | TDP1 (0.45) | LMNACES2CES1MAPK1ALDH1A1 | |
| SCHEMBL19358709 | 0.77 | LMNA (0.42) | LMNACES2CES1MAPK1ALDH1A1 | |
| SCHEMBL304470 | 0.77 | CASP6 (0.55) | LMNACES2ALDH1A1KDM4EGPR35 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7208148-B2 | Chemically modified cytokines | NEOVACS S.A. (FR) | 2007-04-24 | — | — | US | claimed |
| US-20050180950-A1 | Chemically modified TNF-alpha | NEOVACS (FR) | 2005-08-18 | — | — | US | claimed |
| CN-113149844-B | Novel synthesis process of 2,4,6-trinitrobenzoic acid | 中北大学 | 2023-03-31 | — | — | CN | disclosed |
| CN-113149844-A | Novel synthesis process of 2,4, 6-trinitrobenzoic acid | 中北大学 | 2021-07-23 | — | — | CN | disclosed |
| CN-106328962-B | Preparation method of composite electro-oxidation catalytic material | 北方工业大学 | 2018-10-23 | — | — | CN | disclosed |
| CN-108291123-A | cellulose acetate wood filler composition | 醋酸纤维国际有限责任公司 | 2018-07-17 | — | — | CN | disclosed |
| CN-108291056-A | cellulose acetate film-forming composition | 醋酸纤维国际有限责任公司 | 2018-07-17 | — | — | CN | disclosed |
| CN-101184797-A | Method for compounding polymer pellets with functional additives | EASTMAN CHEM CO (US) | 2008-05-21 | — | — | CN | disclosed |
| EP-0983267-A1 | AMIDOAROMATIC RING SULFONAMIDE HYDROXAMIC ACID COMPOUNDS | MONSANTO COMPANY (US) | 2000-03-08 | — | — | EP | disclosed |
| WO-1998039329-A1 | AMIDOAROMATIC RING SULFONAMIDE HYDROXAMIC ACID COMPOUNDS | MONSANTO COMPANY (US) | 1998-09-11 | — | — | WO | disclosed |