Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 3/20 | 0.43 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.40 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.40 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.40 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.40 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.40 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.39 |
| ▸ | THRA | P10827 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 4/20 | 0.39 |
| ▸ | PPARD | Q03181 | 5/20 | 0.38 |
| ▸ | PPARA | Q07869 | 5/20 | 0.38 |
| ▸ | RXRA | P19793 | 1/20 | 0.38 |
| ▸ | RXRB | P28702 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27697446 | 0.70 | THRB (0.49) | THRBPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL8329343 | 0.69 | LTA4H (0.60) | THRBPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL27697443 | 0.69 | THRB (0.51) | THRBPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL27697439 | 0.69 | THRB (0.51) | THRBPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL1407164 | 0.68 | PPARG (0.42) | KDM4EPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL28394422 | 0.67 | CXCL8 (0.57) | THRBFFAR1PPARGPPARDPPARA | |
| SCHEMBL30740359 | 0.66 | SCN9A (0.41) | KDM4EALDH1A1HPGDHSD17B10PPARG | |
| SCHEMBL21225736 | 0.66 | SCN9A (0.41) | KDM4EALDH1A1HPGDHSD17B10PPARG | |
| SCHEMBL11077637 | 0.66 | THRB (0.60) | THRBFFAR1THRASMN1; SMN2PPARG | |
| SCHEMBL4597814 | 0.65 | PSEN1 (0.58) | THRBPSEN1PSEN2APH1BNCSTN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101142185-A | Indoles useful in the treatment of inflammation | BIOLIPOX AB (SE) | 2008-03-12 | — | — | CN | disclosed |