Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 7/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 6/20 | 0.39 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.38 |
| ▸ | AURKA | O14965 | 1/20 | 0.38 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30015045 | 0.71 | ALDH1A1 (0.54) | RAB9ASMN1; SMN2NPC1ALDH1A1PKM | |
| SCHEMBL28423225 | 0.70 | AURKA (0.44) | AURKAAURKB | |
| Acetic Acid SCHEMBL28893671 | 0.69 | CYP1A2 (0.50) | KMT2ARAB9ASMN1; SMN2NPC1MEN1 | |
| SCHEMBL27718208 | 0.69 | NNMT (0.36) | — | |
| SCHEMBL5888996 | 0.68 | POLB (0.43) | KMT2AMAPTRAB9ASMN1; SMN2MAPK1 | |
| SCHEMBL27913740 | 0.68 | ADORA3 (0.45) | — | |
| SCHEMBL3350408 | 0.67 | SMPD3 (0.46) | KMT2AMAPTMAPK1MEN1ALDH1A1 | |
| SCHEMBL2066542 | 0.66 | KMT2A (0.40) | KMT2AMAPTRAB9ASMN1; SMN2MAPK1 | |
| SCHEMBL341998 | 0.66 | SMN1; SMN2 (0.40) | KMT2AMAPTRAB9ASMN1; SMN2MAPK1 | |
| SCHEMBL2729192 | 0.66 | CHEK2 (0.40) | KMT2AMAPTRAB9ASMN1; SMN2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101103017-A | Novel aminopyridine derivatives having Aurora-A selective inhibitory action | BANYU PHARMA CO LTD (JP) | 2008-01-09 | — | — | CN | disclosed |