Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.30 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.30 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.30 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.30 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.30 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.30 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27701649 | 0.87 | HDAC1 (0.37) | PKMHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL27722334 | 0.85 | HDAC6 (0.36) | PKMHDAC3HDAC1HDAC7HDAC2 | |
| SCHEMBL27722222 | 0.78 | ALDH1A1 (0.39) | PKMALDH1A1HTT | |
| SCHEMBL27701908 | 0.74 | GRIN1 (0.33) | HDAC1ALDH1A1HTT | |
| SCHEMBL27722262 | 0.73 | KMT2A (0.40) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL27701734 | 0.72 | SMN1; SMN2 (0.41) | HDAC8ALDH1A1HTT | |
| SCHEMBL27701899 | 0.69 | GPR139 (0.33) | PKMALDH1A1 | |
| SCHEMBL27722220 | 0.68 | KDM4E (0.39) | ALDH1A1 | |
| SCHEMBL27701782 | 0.68 | NRP1 (0.32) | — | |
| SCHEMBL27722226 | 0.68 | HDAC1 (0.39) | HDAC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101163703-B | Imidazo [1,2-A ] pyridine derivatives as Peptide Deformylase (PDF) inhibitors | NOVARTIS AG | 2010-12-15 | — | — | CN | disclosed |
| CN-101163703-A | Imidazo [1, 2-A ] pyridine derivatives as Peptide Deformylase (PDF) inhibitors | NOVARTIS AG (CH) | 2008-04-16 | — | — | CN | disclosed |