SCHEMBL27722751

SCHEMBL27722751

C=C(C)C(=O)N1C(=O)C=CC1=O

nearest known ligand 0.36

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 2/20 0.36
GSK3A P49840 2/20 0.36
GSK3B P49841 2/20 0.36
ALDH1A1 P00352 2/20 0.32
BLM P54132 2/20 0.32
CYP1A2 P05177 1/20 0.32
HPGD P15428 1/20 0.32
CYP2C19 P33261 1/20 0.32
WRN Q14191 1/20 0.32
HIF1A Q16665 1/20 0.32
GMNN O75496 1/20 0.32
LMNA P02545 1/20 0.32
MAPT P10636 1/20 0.32
THPO P40225 1/20 0.32
PMP22 Q01453 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
PTGS1 P23219 4/20 0.31
PTGS2 P35354 4/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10778001 0.86
SCHEMBL4857568 0.77 MGLL (0.41) MGLLGSK3AGSK3BALDH1A1BLM
SCHEMBL12038009 0.76 ALDH1A1 (0.36) MGLLGSK3AGSK3BALDH1A1BLM
SCHEMBL21235975 0.76 PTGS1 (0.31) MGLLGSK3AGSK3BPTGS1PTGS2
SCHEMBL720720 0.74 MGLL (0.43) MGLLGSK3AGSK3BALDH1A1BLM
SCHEMBL1530917 0.71 KMT2A (0.40) BLMTDP1
SCHEMBL330062 0.71 ALDH1A1 (0.53) ALDH1A1HPGDLMNA
Methacrylic Acid SCHEMBL2479561 0.70 MGLL (0.59) MGLLGSK3AGSK3BALDH1A1BLM
SCHEMBL18485409 0.68 P2RX4 (0.42) MGLLGSK3AGSK3BALDH1A1BLM
SCHEMBL7110683 0.68 DDAH1 (0.34) MGLLGSK3AGSK3BPTGS1PTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105385362-B Adhesive composition and connection structure 日立化成株式会社 2020-05-15 CN disclosed
CN-104053681-B Thermally expandable microspheres, process for producing the same, and use thereof MATSUMOTO YUSHI-SEIYAKU CO.,LTD. (JP) 2015-11-25 CN disclosed
CN-104053681-A Thermally expandable microspheres, process for producing the same, and use thereof YOKOHAMA RUBBER CO LTD 2014-09-17 CN disclosed
CN-101312782-B Heat-expandable microsphere, process for producing the same, and use YOKOHAMA RUBBER CO LTD 2012-07-11 CN disclosed
CN-101679537-B Process for production of thermally expandable beads and application thereof MATSUMOTO YUSHI SEIYAKU KK 2012-01-04 CN disclosed
CN-101679537-A Process for production of thermally expandable beads and application thereof MATSUMOTO YUSHI SEIYAKU KK 2010-03-24 CN disclosed
CN-101312782-A Heat-expandable microsphere, process for producing the same, and use MATSUMOTO YUSHI SEIYAKU KK (JP) 2008-11-26 CN disclosed