Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.51 |
| ▸ | MCL1 | Q07820 | 6/20 | 0.51 |
| ▸ | BAD | Q92934 | 6/20 | 0.51 |
| ▸ | CNR2 | P34972 | 6/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | GALR3 | O60755 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | APAF1 | O14727 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27707847 | 0.85 | RAB9A (0.47) | RAB9ANPC1NOD2CNR2MAPT | |
| SCHEMBL27707858 | 0.84 | RAB9A (0.51) | RAB9ANPC1NOD2CNR2MAPT | |
| SCHEMBL27707843 | 0.81 | TP53 (0.63) | RAB9ANPC1NOD2CNR2MAPT | |
| SCHEMBL27728428 | 0.81 | RAB9A (0.51) | RAB9ANPC1NOD2MAPTL3MBTL1 | |
| SCHEMBL28215959 | 0.81 | L3MBTL1 (0.66) | RAB9ACNR2MAPTL3MBTL1KDM4E | |
| SCHEMBL21999706 | 0.79 | LMNA (0.69) | MCL1BADCNR2 | |
| SCHEMBL6802019 | 0.78 | ALDH1A1 (0.70) | RAB9ANPC1MAPTL3MBTL1KDM4E | |
| SCHEMBL28229359 | 0.77 | NR4A2 (0.64) | CNR2L3MBTL1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL27728387 | 0.76 | POLB (0.72) | CNR2MAPTL3MBTL1NPSR1ALDH1A1 | |
| SCHEMBL28155884 | 0.75 | SLC22A12 (0.60) | RAB9ANPC1NOD2CNR2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101213174-A | Oxindole compounds and their uses as therapeutic agents | XENON PHARMACEUTICALS INC (CA) | 2008-07-02 | — | — | CN | disclosed |