SCHEMBL27730889

SCHEMBL27730889

[H+].[SiH3]C1(C(Cc2ccccc2)C2([SiH3])CCCCO2)CCCCO1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
EPHX1 P07099 1/20 0.33
ITGB1 P05556 6/20 0.33
ITGA4 P13612 6/20 0.33
MMP1 P03956 1/20 0.33
ALPI P09923 1/20 0.33
PKM P14618 1/20 0.33
PTGS1 P23219 1/20 0.33
XIAP P98170 1/20 0.33
SLC7A5 Q01650 1/20 0.33
GAA P10253 1/20 0.32
MAPK1 P28482 1/20 0.32
TMEM97 Q5BJF2 1/20 0.32
SIGMAR1 Q99720 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP3A4 P08684 1/20 0.32
CYP2D6 P10635 1/20 0.32
TSHR P16473 1/20 0.32
CYP2C19 P33261 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3480881 0.98 EPHX1 (0.34) MEN1KMT2AEPHX1ITGB1ITGA4
SCHEMBL9015220 0.84 SIGMAR1 (0.37) MEN1KMT2AGAAMAPK1SIGMAR1
SCHEMBL9720288 0.83 SLC6A2 (0.36) MEN1KMT2AEPHX1MMP1TMEM97
SCHEMBL28119517 0.77 MEN1 (0.33) MEN1KMT2A
SCHEMBL3219070 0.75 MEN1 (0.33) MEN1KMT2AGAAMAPK1TSHR
SCHEMBL28009306 0.75 MEN1 (0.33) MEN1KMT2AGAAMAPK1TSHR
SCHEMBL28680577 0.74 LMNA (0.32) MEN1KMT2ACYP3A4CYP2D6TSHR
SCHEMBL27668036 0.73 MAOA (0.40) TMEM97SIGMAR1
SCHEMBL17024087 0.73 OPRM1 (0.33) MEN1KMT2ACYP1A2CYP2D6TSHR
SCHEMBL28497539 0.72 L3MBTL1 (0.33) MEN1KMT2ACYP1A2CYP2D6TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101356227-B Rubber compound FREUDENBERG CARL KG 2012-07-11 CN claimed
CN-101365749-A Elastomer blend FREUDENBERG CARL KG (DE) 2009-02-11 CN claimed
CN-101356227-A Rubber compound FREUDENBERG CARL KG (DE) 2009-01-28 CN claimed
CN-101317291-A Use of elastomer blends as materials in the insertion region of fuel cells FREUDENBERG CARL KG (DE) 2008-12-03 CN claimed
CN-104884098-A Medical sealant composition and method of use thereof 3M INNOVATIVE PROPERTIES CO 2015-09-02 CN disclosed
CN-103319895-A Silicone composition with improved mechanical properties SIKA TECHNOLOGY AG 2013-09-25 CN disclosed
CN-101356227-B Rubber compound FREUDENBERG CARL KG 2012-07-11 CN disclosed
CN-101317291-B Use of elastomer blends as materials in the insertion region of fuel cells NOK CORP. (JP) 2011-12-21 CN disclosed
CN-101365749-B Elastomer blend FREUDENBERG CARL KG 2011-07-27 CN disclosed
CN-101365749-A Elastomer blend FREUDENBERG CARL KG (DE) 2009-02-11 CN disclosed
CN-101356227-A Rubber compound FREUDENBERG CARL KG (DE) 2009-01-28 CN disclosed
CN-101317291-A Use of elastomer blends as materials in the insertion region of fuel cells FREUDENBERG CARL KG (DE) 2008-12-03 CN disclosed