Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 1/20 | 0.42 |
| ▸ | PGR | P06401 | 1/20 | 0.42 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | MPL | P40238 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | KIF11 | P52732 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27713342 | 0.90 | HRH4 (0.44) | NR3C1ALDH1A1GAAL3MBTL1MEN1 | |
| SCHEMBL24380299 | 0.77 | KIF11 (0.45) | NR3C1PGRNR3C2ALDH1A1MEN1 | |
| SCHEMBL3526963 | 0.77 | MTNR1A (0.45) | NR3C1PGRNR3C2GSK3BALDH1A1 | |
| SCHEMBL27733721 | 0.75 | KDM4E (0.47) | NR3C1PGRNR3C2ALDH1A1KDM4E | |
| SCHEMBL23932536 | 0.74 | METAP2 (0.45) | NR3C1PGRNR3C2MPLKIF11 | |
| SCHEMBL3422658 | 0.74 | PTGDR2 (0.46) | NR3C1PGRNR3C2MPLALDH1A1 | |
| SCHEMBL2139103 | 0.74 | ALOX15 (0.65) | ALDH1A1GAAL3MBTL1MEN1KMT2A | |
| SCHEMBL29619390 | 0.74 | ALOX15 (0.65) | ALDH1A1GAAL3MBTL1MEN1KMT2A | |
| Lithium Ion SCHEMBL3422654 | 0.73 | NR3C1 (0.40) | NR3C1PGRNR3C2MPLKIF11 | |
| SCHEMBL27713368 | 0.73 | ALDH1A1 (0.35) | ALDH1A1GAAMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101248044-B | Indole compounds | FOURNIER LAB SA | 2012-05-30 | — | — | CN | disclosed |
| CN-101248044-A | Novel indole compounds | FOURNIER LAB SA (FR) | 2008-08-20 | — | — | CN | disclosed |