Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | KCNA5 | P22460 | 3/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1934716 | 0.82 | ALDH1A1 (0.50) | ALDH1A1TSHRKCNA5 | |
| SCHEMBL6947156 | 0.80 | CASP1 (0.53) | ALDH1A1TSHR | |
| SCHEMBL19712331 | 0.79 | ALDH1A1 (0.50) | ALDH1A1TSHRKCNA5ALOX15IDO1 | |
| SCHEMBL9506098 | 0.78 | L3MBTL1 (0.53) | ALDH1A1TSHR | |
| SCHEMBL1929687 | 0.78 | ALOX12 (0.54) | ALDH1A1TSHRKCNA5ALOX15IDO1 | |
| SCHEMBL20997478 | 0.78 | ALOX12 (0.54) | ALDH1A1TSHRKCNA5ALOX15IDO1 | |
| SCHEMBL28516086 | 0.77 | L3MBTL1 (0.55) | ALDH1A1 | |
| Hydrochloric Acid SCHEMBL6606867 | 0.76 | ALOX12 (0.53) | ALDH1A1TSHRKCNA5ALOX15IDO1 | |
| SCHEMBL9781910 | 0.76 | ALDH1A1 (0.47) | ALDH1A1TSHR | |
| SCHEMBL9189776 | 0.76 | ALDH1A1 (0.47) | ALDH1A1TSHRKCNA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9163033-B2 | Nitrogen-containing heterocyclic compounds and methods of making the same | BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION, ON BEHALF OF THE UNIVERSITY OF NEVADA, RENO (US) | 2015-10-20 | — | — | US | disclosed |
| US-20140350246-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUNDS AND METHODS OF MAKING THE SAME | BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION, ON BEHALF OF THE UNIVERSITY OF NEVADA (US) | 2014-11-27 | — | — | US | disclosed |
| US-20120271046-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUNDS AND METHODS OF MAKING THE SAME | BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION, ON BEHALF OF THE UNIVERSITY OF NEVADA, RENO | 2012-10-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120271046-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUNDS AND METHODS OF MAKING THE SAME | NISCH, HDHD5, DHPS | ALDH1A1 582/4885TSHR 3313/4885KCNA5 1070/4885 |
| US-20140350246-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUNDS AND METHODS OF MAKING THE SAME | NISCH, HDHD5, DHPS | ALDH1A1 582/4885TSHR 3313/4885KCNA5 1070/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.