Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP7 | O15540 | 4/20 | 0.42 |
| ▸ | FABP5 | Q01469 | 4/20 | 0.42 |
| ▸ | PREP | P48147 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27733749 | 0.85 | ALDH1A1 (0.38) | PREPALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9180507 | 0.81 | FABP7 (0.40) | FABP7FABP5PREPALDH1A1NPC1 | |
| SCHEMBL5871291 | 0.69 | NPC1 (0.39) | ALDH1A1NPC1RAB9ASMN1; SMN2CYP2C19 | |
| SCHEMBL13386604 | 0.68 | ALDH1A1 (0.55) | ALDH1A1 | |
| SCHEMBL6262331 | 0.68 | NPC1 (0.37) | ALDH1A1NPC1RAB9ASMN1; SMN2HTR2C | |
| SCHEMBL7448545 | 0.66 | SMN1; SMN2 (0.53) | PREPALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL29191411 | 0.65 | SMN1; SMN2 (0.49) | ALDH1A1NPC1RAB9ASMN1; SMN2GAA | |
| SCHEMBL28775111 | 0.65 | ALDH1A1 (0.46) | PREPALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7543136 | 0.65 | MEN1 (0.36) | PREPALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7415044 | 0.65 | ALDH1A1 (0.39) | ALDH1A1SMN1; SMN2HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5266569-A | Azatricyclo carboxylic acids useful as anti-bacterial agents | PFIZER INC. (US) | 1993-11-30 | — | — | US | disclosed |
| EP-0413455-A2 | Azabicyclo quinolone carboxylic acids | PFIZER INC. (US) | 1991-02-20 | — | — | EP | disclosed |